Proper knowledge of an aquifer system is prerequisite for its utilization, protection from pollution, and sustainable development. The sections of this chapter provide an overview of main aspects, which must be surveyed and recognized for proper characterization of a karstic aquifer: aquifer geometry and elements, permeability and storativity, flow types and pattern, aquifer recharge, aquifer discharge, quality of karst groundwater. Based on rich literature (82 listed references) and its evaluation sometimes including contradictory theories and approaches, main principles of karst aquifer hydrodynamics and karstic groundwater flow and storage are explained. Numerous classifications are also given. They consider aquifer properties such as po...