IMPACT OF COVID-19 INFECTION ON COURSE OF PREGNANCY

COVID-19 je infekcija uzrokovana novim koronavirusom nazvanim SARS-CoV-2. Virus se kod ljudi prvi put pojavio u prosincu 2019. god. u Wuhanu, u kineskoj provinciji Hubei te se vrlo brzo proširio svijetom predstavljajući veliki izazov zdravstvenim institucijama. Svjetska zdravstvena organizacija (SZO) je 11. ožujka 2020. god. službeno proglasila globalnu pandemiju. Prvi slučaj bolesti u Republici Hrvatskoj dijagnosticiran je krajem veljače 2020. god., a do rujna 2021. god. inficirano je oko 372 000 ljudi od kojih je preko 8 300 umrlo. Budući da se radi o novootkrivenom virusu još je uvijek puno nepoznanica o bolesti koju uzrokuje, kako u općoj populaciji tako i u trudnica. Dosadašnja saznanja ukazuju da je klinički tijek bolesti u trudnica sličan onome u općoj populaciji, a vrlo rijetko COVID-19 pozitivne trudnice imaju tešku kliničku sliku bolesti. Zabilježen je vrlo mali rizik za vertikalni prijenos infekcije s majke na plod. S obzirom da je riječ o novom virusu, zbog predostrožnosti trudnice se uključuju u skupinu umjerenog rizika. Cilj ovog rada je istražiti utjecaj COVID-19 infekcije na tijek i ishod trudnoće. Ovom retrospektivnom kohortnom studijom obuhvaćeno je 30 COVID-19 inficiranih trudnica te jednak broj neinficiranih trudnica.COVID-19 is a disease caused by a new corona virus called SARS-CoV-2. The virus spread very quickly around the world and presented a major challenge to all healthcare institutions. The virus appeared in humans in December 2019 in Wuhan, in the Chinese province of Hubei. World Health Organization (WHO) March 11, 2020 declared a global pandemic (2). The first case in the Republic of Croatia was diagnosed at the end of February 2020, and by Septembre 2021, about 372 000 people were infected, out of whom over 8 300 died. As this is a newly discovered virus, as well as the disease it causes, great efforts are still being made to find an effective drug / vaccine. There is still a lot of information missing about COVID-19 and pregnancy. For now, the clinical course of the disease in pregnant women is known to be similar to that in the general population. The poor outcome of the virus in the course and outcome of pregnancy has not yet been proven, and there is no conclusive evidence of vertical transmission through breast milk. In this retrospective cohort study 30 infected pregnant women with COVID-19 and an equal number of uninfected pregnant women were included. The aim of this study was to investigate the impact of COVID-19 infection on course and outcome of pregnanc