Cardiovascular diseases (CVDs) are typically caused by multifactorial events including mutations in a large number of genes. Epigenetic-derived modifications in the cells are normal but can be amended by aging, lifestyle, and exposure to toxic substances. Major epigenetic modifications are DNA methylation, histone modification, chromatin remodeling as well as the noncoding RNAs. These pivotal players are involved in the epigenetic-induced modifications observed during CVDs. Nevertheless, despite impressive efforts capitalized in epigenetic research in the last 50 years, clinical applications are still not satisfactory
Epigenetic phenomena define heritable mechanisms that establish and maintain mitotically stable patt...
A plethora of environmental and behavioral factors interact, resulting in changes in gene expression...
AbstractBackgroundEpigenetic modifications of the genome, such as DNA methylation and histone modifi...
Mortality and morbidity from cardiovascular diseases (CVDs) represents a huge burden to society. It ...
The study of epigenomics has advanced in recent years to span the regulation of a single genetic loc...
International audienceEpigenetic sciences study heritable changes in gene expression not related to ...
Despite significant advances in our understanding of cardiovascular disease (CVD) we are still far f...
Notwithstanding the intense efforts into the understanding and prevention of cardiovascular disease ...
A plethora of environmental and behavioral factors interact, resulting in changes in gene expression...
Epigenetics is defined as the study of inheritable changes in the gene expressions and phenotypes th...
If unifying principles could be revealed for how the same genome encodes different eukaryotic cells ...
Epigenetics, through control of gene expression circuitries, plays important roles in various physio...
© 2015 Elsevier Ireland Ltd. All rights reserved. Background Epigenetic modifications of the genome,...
_Background:_ Epigenetic modifications of the genome, such as DNA methylation and histone modificati...
A growing body of evidence suggests that epigenetic modifications-changes to the genome that do not ...
Epigenetic phenomena define heritable mechanisms that establish and maintain mitotically stable patt...
A plethora of environmental and behavioral factors interact, resulting in changes in gene expression...
AbstractBackgroundEpigenetic modifications of the genome, such as DNA methylation and histone modifi...
Mortality and morbidity from cardiovascular diseases (CVDs) represents a huge burden to society. It ...
The study of epigenomics has advanced in recent years to span the regulation of a single genetic loc...
International audienceEpigenetic sciences study heritable changes in gene expression not related to ...
Despite significant advances in our understanding of cardiovascular disease (CVD) we are still far f...
Notwithstanding the intense efforts into the understanding and prevention of cardiovascular disease ...
A plethora of environmental and behavioral factors interact, resulting in changes in gene expression...
Epigenetics is defined as the study of inheritable changes in the gene expressions and phenotypes th...
If unifying principles could be revealed for how the same genome encodes different eukaryotic cells ...
Epigenetics, through control of gene expression circuitries, plays important roles in various physio...
© 2015 Elsevier Ireland Ltd. All rights reserved. Background Epigenetic modifications of the genome,...
_Background:_ Epigenetic modifications of the genome, such as DNA methylation and histone modificati...
A growing body of evidence suggests that epigenetic modifications-changes to the genome that do not ...
Epigenetic phenomena define heritable mechanisms that establish and maintain mitotically stable patt...
A plethora of environmental and behavioral factors interact, resulting in changes in gene expression...
AbstractBackgroundEpigenetic modifications of the genome, such as DNA methylation and histone modifi...