A 10 km time trial running bout acutely increases the number of angiogenic T cells in the peripheral blood compartment of healthy males: Acute exercise mobilizes angiogenic T cells

New FindingsWhat is the central question of the study?Are CD31+ angiogenic T (TANG) cells preferentially mobilized in response to acute exercise?What is the main finding and its importance?Our study reveals that TANG cells are redistributed into the circulation in response to acute strenuous exercise, but to a lesser extent than CD31− T cells. Of the TANG cells mobilized, TANG cells expressing CXCR4 show greater redistribution compared with CXCR4− TANG cells. Stromal-derived factor 1-α does not appear to play a role in the redistribution of TANG cells expressingCXCR4. The results suggest that a single bout of strenuous exercise might provide a short vasculogenic window, which could benefit the vascular systemby redistributing CD31+ TANG cells