A microfluidic chip with a nanoscale array for analysis of virus particles

In this work, an individually addressable nano-probe array within a micro-fluidic channel is developed. The probe array captured the viral particles from fluid flow with dielectrophoresis (DEP) force and the same probes are then used to investigate the effect of strong electric field on the virus particles. A number of biologically important particles, such as vaccinia virus, lambda virus and polystyrene beads can be captured, and can be conveniently observed via optical microscope. © 2006 Society for Chemistry and Micro-Nano Systems