To study possible interactions between dopamine (DA) and serotonin (5-HT) neurochemical systems in the D-1 supersensitized induction of oral activity in neonatal 6-hydroxydopamine (6-OHDA) lesioned rats, the effects of a series of 5-HT agonists and antagonists were determined. At 3 days after birth rats were treated with desipramine HCl (20 mg/kg i.p., base form, 1 hr) and 6-OHDA HBr (100 μg, salt form, in each lateral ventricle). Rats were observed individually as adults, once a minute every 10 min over a 1-hr period after challenge with a DA or 5-HT receptor agonist. The respective 5-HT(1A) and 5- HT(1B) agonists, (±)-8-hydroxydipropylaminotetralin (0.50 mg/kg s.c.) and CGS 12066B maleate (7-trifluoromethyl-4(4-methyl-1-piperazinyl)-pyrro...
Abstract: To study potential biochemical correlates of dopamine (DA) and serotonin receptor supersen...
Dopamine (DA) receptor supersensitivity refers to the phenomenon of an enhanced physiological, behav...
To explore associations of neostriatal (NST) endogenous levels of dopamine (DA) and serotonin (5-HT)...
Neonatal 6-hydroxydopamine (6-OHDA) treatment of rats is associated with supersensitization of the d...
5-Hydroxytryptamine (5-HT) 5-HT(2c) receptors mediate the enhanced oral activity response to the dop...
Neonatal 6-hydroxydopamine (6-OHDA) treatment of rats is associated with concurrent supersensitizati...
Enhanced oral activity is induced in neonatal 6-hydroxydopamine- (6-OHDA-) lesioned rats by systemic...
Ontogenetic dopaminergic denervation of rat forebrain is associated with latent supersensitization o...
To test whether SKF 38393 could ontogenetically sensitize dopamine (DA) D$\sb1$ receptors and whethe...
The ontogenic destruction of dopamine (DA) neurons in rat brain is associated with supersensitizatio...
Neonatal 6-hydroxydopamine (6-OHDA) treatment is associated with destruction of dopamine (DA) fibers...
Enhanced oral responses have been observed in rats that are treated shortly after birth with 6-hydro...
To study the role of dopamine D1 receptors in enhanced oral activity effects of SKF 38393 ((±)-1-phe...
In rat, the neonatal destruction of nigrostriatal dopamine (DA) neurons by intracerebral administrat...
Neonatal destruction of rat nigrostriatal dopaminergic fibers results in an enhanced oral activity r...
Abstract: To study potential biochemical correlates of dopamine (DA) and serotonin receptor supersen...
Dopamine (DA) receptor supersensitivity refers to the phenomenon of an enhanced physiological, behav...
To explore associations of neostriatal (NST) endogenous levels of dopamine (DA) and serotonin (5-HT)...
Neonatal 6-hydroxydopamine (6-OHDA) treatment of rats is associated with supersensitization of the d...
5-Hydroxytryptamine (5-HT) 5-HT(2c) receptors mediate the enhanced oral activity response to the dop...
Neonatal 6-hydroxydopamine (6-OHDA) treatment of rats is associated with concurrent supersensitizati...
Enhanced oral activity is induced in neonatal 6-hydroxydopamine- (6-OHDA-) lesioned rats by systemic...
Ontogenetic dopaminergic denervation of rat forebrain is associated with latent supersensitization o...
To test whether SKF 38393 could ontogenetically sensitize dopamine (DA) D$\sb1$ receptors and whethe...
The ontogenic destruction of dopamine (DA) neurons in rat brain is associated with supersensitizatio...
Neonatal 6-hydroxydopamine (6-OHDA) treatment is associated with destruction of dopamine (DA) fibers...
Enhanced oral responses have been observed in rats that are treated shortly after birth with 6-hydro...
To study the role of dopamine D1 receptors in enhanced oral activity effects of SKF 38393 ((±)-1-phe...
In rat, the neonatal destruction of nigrostriatal dopamine (DA) neurons by intracerebral administrat...
Neonatal destruction of rat nigrostriatal dopaminergic fibers results in an enhanced oral activity r...
Abstract: To study potential biochemical correlates of dopamine (DA) and serotonin receptor supersen...
Dopamine (DA) receptor supersensitivity refers to the phenomenon of an enhanced physiological, behav...
To explore associations of neostriatal (NST) endogenous levels of dopamine (DA) and serotonin (5-HT)...