Sperm cell (SC) lineage development from the haploid microspore to SCs represents a unique biological process in which the microspore generates a larger vegetative cell (VC) and a smaller generative cell (GC) enclosed in the VC, then the GC further develops to functionally specified SCs in the VC for double fertilization. Understanding the mechanisms of SC lineage development remains a critical goal in plant biology. We isolated individual cells of the three cell types, and characterized the genome-wide atlas of long non-coding (lnc) RNAs and mRNAs of haploid SC lineage cells. Sperm cell lineage development involves global repression of genes for pluripotency, somatic development and metabolism following asymmetric microspore division and c...
<div><p>A recently developed strategy of sequencing alternative polyadenylation (APA) sites (SAPAS) ...
(1A) Immunofluorescence of FGFR3 (red) co-stained with DDX4, UTF1, KIT, or STRA8 (green) in adult hu...
International audienceSertoli cells (SCs), the only somatic cells within seminiferous tubules, assoc...
Spermatogenesis is a dynamic developmental process that includes stem cell proliferation and differe...
The male germ cell undergoes a proliferative step of amplification of the cell number, a meiotic ste...
Summary: Spermatogenesis is a complex and dynamic cellular differentiation process critical to male ...
<div><p>Increasing studies have shown that mature spermatozoa contain many transcripts including mRN...
Spermatogenesis is the process by which male gametes are formed from a self-renewing population of s...
dissertationHuman spermatogonial stem cells (SSCs) are the only stem cells in the male germline, whi...
Increasing studies have shown that mature spermatozoa contain many transcripts including mRNAs and m...
Many long noncoding RNA (lncRNA) species have been identified in gametes. However, the biogenesis an...
Spermatogenesis is the process by which male gametes are formed from a self-renewing population of s...
Spermatogonial stem cells (SSCs) play fundamental roles in spermatogenesis. Although a handful of ge...
International audienceSTUDY QUESTION - Is the noncoding transcriptional landscape during spermatogen...
International audienceMammalian spermatogenesis is a complex and highly orchestrated combination of ...
<div><p>A recently developed strategy of sequencing alternative polyadenylation (APA) sites (SAPAS) ...
(1A) Immunofluorescence of FGFR3 (red) co-stained with DDX4, UTF1, KIT, or STRA8 (green) in adult hu...
International audienceSertoli cells (SCs), the only somatic cells within seminiferous tubules, assoc...
Spermatogenesis is a dynamic developmental process that includes stem cell proliferation and differe...
The male germ cell undergoes a proliferative step of amplification of the cell number, a meiotic ste...
Summary: Spermatogenesis is a complex and dynamic cellular differentiation process critical to male ...
<div><p>Increasing studies have shown that mature spermatozoa contain many transcripts including mRN...
Spermatogenesis is the process by which male gametes are formed from a self-renewing population of s...
dissertationHuman spermatogonial stem cells (SSCs) are the only stem cells in the male germline, whi...
Increasing studies have shown that mature spermatozoa contain many transcripts including mRNAs and m...
Many long noncoding RNA (lncRNA) species have been identified in gametes. However, the biogenesis an...
Spermatogenesis is the process by which male gametes are formed from a self-renewing population of s...
Spermatogonial stem cells (SSCs) play fundamental roles in spermatogenesis. Although a handful of ge...
International audienceSTUDY QUESTION - Is the noncoding transcriptional landscape during spermatogen...
International audienceMammalian spermatogenesis is a complex and highly orchestrated combination of ...
<div><p>A recently developed strategy of sequencing alternative polyadenylation (APA) sites (SAPAS) ...
(1A) Immunofluorescence of FGFR3 (red) co-stained with DDX4, UTF1, KIT, or STRA8 (green) in adult hu...
International audienceSertoli cells (SCs), the only somatic cells within seminiferous tubules, assoc...