Effects of On-Arrival Application of a Modified-Live Respiratory and Clostridia Vaccination on Health, Growth Performance, and Antibody Titers of Newly-Weaned Calves

Study Description: Single-sourced, newly weaned steers (n=70; initial body weight (BW)=560±12.9lb) were allotted to 10 pens (n=5 pens/treatment with 7 steers/pen). Steers were blocked by BW in a randomized complete block design of VAC [vaccinated for IBR, BVD 1 and 2, PI3, and BRSV (Bovi-Shield Gold 5, Zoetis, Parsippany, NJ) and clostridial (Ultrabec 7/Somubac, Zoetis) upon arrival] or NOVAC (not vaccinated for IBR, BVD 1 and 2, PI3, and BRSV or clostridial species upon arrival). Steers were individually weighed on d 0 (arrival), 1, 21, and 42 for growth performance measures. Whole blood samples (10 mL) were collected (n=3 steers/pen closest to the pen mean BW) on d 1, 21, and 42 via jugular venipuncture for metabolite and antibody titer responses