Perfusion Imaging for Endovascular Thrombectomy in Acute Ischemic Stroke Is Associated With Improved Functional Outcomes in the Early and Late Time Windows.
- Dhillon, Permesh Singh
- Butt, Waleed
- Podlasek, Anna
- McConachie, Norman
- Lenthall, Robert
- Nair, Sujit
- Malik, Luqman
- Booth, Thomas C
- Bhogal, Pervinder
- Makalanda, Hegoda Levansri Dilrukshan
- Spooner, Oliver
- Mortimer, Alex
- Lamin, Saleh
- Chavda, Swarupsinh V
- Chew, Han Seng
- Nader, Kurdow
- Al-Ali, Samer
- Butler, Benjamin
- Rajapakse, Dilina
- Appleton, Jason P
- Krishnan, Kailash
- Sprigg, Nikola
- Smith, Aubrey
- Lobotesis, Kyriakos
- White, Phil
- James, Martin A
- Bath, Philip M
- Dineen, Robert A
- England, Timothy J
DOIAbstract
BACKGROUND The impact on clinical outcomes of patient selection using perfusion imaging for endovascular thrombectomy (EVT) in patients with acute ischemic stroke presenting beyond 6 hours from onset remains undetermined in routine clinical practice. METHODS Patients from a national stroke registry that underwent EVT selected with or without perfusion imaging (noncontrast computed tomography/computed tomography angiography) in the early (<6 hours) and late (6-24 hours) time windows, between October 2015 and March 2020, were compared. The primary outcome was the ordinal shift in the modified Rankin Scale score at hospital discharge. Other outcomes included functional independence (modified Rankin Scale score ≤2) and in-hospital mort...
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