In spatial planning, there is an increasing awareness that uncertainty must be taken into account in decision-making. At the same time, it appears to be difficult to include uncertainty in decision-making due to the interaction between policymakers and other actors, and because of a changing environment during the decision-making process. This research examines the way policy makers deal with uncertainty in infrastructure planning under the influence of the aforementioned factors. To this end, the decision-making process for three area-oriented infrastructure projects is analyzed: the redevelopment of Airport Twente, the construction of a bypass of the IJssel River near Kampen, and the redevelopment of the provincial road N340 Zwolle-Ommen....