Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, especially under hypoxia. ROS are also enzymatically generated at the plasma membrane during inflammation. Radicals cause cellular damage leading to cell death, as they react indiscriminately with surrounding lipids, proteins, and nucleotides. However, ROS are also important for many physiological processes, including signaling, pathogen killing and chemotaxis. The sensitivity of cells to ROS therefore likely depends on the subcellular location of ROS production, but how this affects cell viability is poorly understood. As ROS generation consumes oxygen, and hypoxia-mediated signaling upregulates expression of antioxidant transcription factor Nrf...
Significance: Reactive Oxygen Species (ROS) may regulate signaling, ion channels, transcription fact...
Significance: Reactive Oxygen Species (ROS) may regulate signaling, ion channels, transcription fact...
Generation of reactive oxygen species (ROS) constantly occurs in healthy cells and is inevitable for...
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, espe...
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, espe...
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, espe...
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, espe...
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, espe...
In this issue of Chemistry & Biology, Kelly and colleagues describe the development of two novel ROS...
AbstractReactive oxygen species (ROS) are formed upon incomplete reduction of molecular oxygen (O2) ...
Reactive Oxygen Species (ROS) are known to cause oxidative damage to DNA, proteins and lipids. In ad...
AbstractReactive Oxygen Species (ROS) are known to cause oxidative damage to DNA, proteins and lipid...
There is significant evidence that, in living systems, free radicals and other reactive oxygen and n...
There is significant evidence that, in living systems, free radicals and other reactive oxygen and n...
Significance: Reactive Oxygen Species (ROS) may regulate signaling, ion channels, transcription fact...
Significance: Reactive Oxygen Species (ROS) may regulate signaling, ion channels, transcription fact...
Significance: Reactive Oxygen Species (ROS) may regulate signaling, ion channels, transcription fact...
Generation of reactive oxygen species (ROS) constantly occurs in healthy cells and is inevitable for...
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, espe...
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, espe...
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, espe...
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, espe...
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, espe...
In this issue of Chemistry & Biology, Kelly and colleagues describe the development of two novel ROS...
AbstractReactive oxygen species (ROS) are formed upon incomplete reduction of molecular oxygen (O2) ...
Reactive Oxygen Species (ROS) are known to cause oxidative damage to DNA, proteins and lipids. In ad...
AbstractReactive Oxygen Species (ROS) are known to cause oxidative damage to DNA, proteins and lipid...
There is significant evidence that, in living systems, free radicals and other reactive oxygen and n...
There is significant evidence that, in living systems, free radicals and other reactive oxygen and n...
Significance: Reactive Oxygen Species (ROS) may regulate signaling, ion channels, transcription fact...
Significance: Reactive Oxygen Species (ROS) may regulate signaling, ion channels, transcription fact...
Significance: Reactive Oxygen Species (ROS) may regulate signaling, ion channels, transcription fact...
Generation of reactive oxygen species (ROS) constantly occurs in healthy cells and is inevitable for...