Background: Metabolic syndrome (MetS) is a common complication of long-term treatment of persons with schizophrenia taking (atypical) antipsychotics. In this study, we investigated the existence of an association with polymorphisms of genes for four hormones that regulate energy metabolism. Methods: We recruited 517 clinically admitted white patients (269M/248F) with a verified diagnosis of schizophrenia (ICD-10) and with a stable physical condition. Participants were classified for having or not having MetS and genotyped for 20 single-nucleotide polymorphisms (SNPs) in the genes encoding insulin-induced gene 2 (INSIG2), ghrelin (GHRL), leptin (LEP), and leptin receptor (LEPR). Results: The 139 patients (26.9%) with MetS were significantly ...
Background Schizophrenia is a highly heritable complex psychiatric disorder with an ...
BACKGROUND: Schizophrenia is a highly heritable complex psychiatric disorder with an underlying path...
Most second-generation antipsychotics (SGAs) induce metabolic disturbances, but large differences ex...
Background: Metabolic syndrome (MetS) is a common complication of long-term treatment of persons wit...
Aim: The occurrence of metabolic syndrome (MS) in schizophrenia patients receiving long-term antipsy...
Aim: The occurrence of metabolic syndrome (MS) in schizophrenia patients receiving long-term antipsy...
Background: Antipsychotic-induced metabolic syndrome (MetS) is a multifactorial disease with a genet...
BACKGROUND: Metabolic syndrome is widespread in patients with schizophrenia receiving long-term anti...
Purpose: Metabolic syndrome (MetS) is characterized by abdominal obesity, hyperglycaemia, dyslipidae...
Aim: Second-generation antipsychotics (SGA) are known to induce metabolic disturbances. Genetic path...
Background: Metabolic syndrome (MetS) occupies an important place among the main problems of the som...
Objective: Meta-analyses have implicated polymorphisms in MTHFR, encoding a critical enzyme in folat...
Background Schizophrenia is a highly heritable complex psychiatric disorder with an ...
BACKGROUND: Schizophrenia is a highly heritable complex psychiatric disorder with an underlying path...
Most second-generation antipsychotics (SGAs) induce metabolic disturbances, but large differences ex...
Background: Metabolic syndrome (MetS) is a common complication of long-term treatment of persons wit...
Aim: The occurrence of metabolic syndrome (MS) in schizophrenia patients receiving long-term antipsy...
Aim: The occurrence of metabolic syndrome (MS) in schizophrenia patients receiving long-term antipsy...
Background: Antipsychotic-induced metabolic syndrome (MetS) is a multifactorial disease with a genet...
BACKGROUND: Metabolic syndrome is widespread in patients with schizophrenia receiving long-term anti...
Purpose: Metabolic syndrome (MetS) is characterized by abdominal obesity, hyperglycaemia, dyslipidae...
Aim: Second-generation antipsychotics (SGA) are known to induce metabolic disturbances. Genetic path...
Background: Metabolic syndrome (MetS) occupies an important place among the main problems of the som...
Objective: Meta-analyses have implicated polymorphisms in MTHFR, encoding a critical enzyme in folat...
Background Schizophrenia is a highly heritable complex psychiatric disorder with an ...
BACKGROUND: Schizophrenia is a highly heritable complex psychiatric disorder with an underlying path...
Most second-generation antipsychotics (SGAs) induce metabolic disturbances, but large differences ex...