Clinical paper The effect of immediate coronary angiography after cardiac arrest without ST-segment elevation on left ventricular function. A sub-study of the COACT randomised trial
- Lemkes, Jorrit S.
- Spoormans, Eva M.
- Demirkiran, Ahmet
- Leutscher, Sophie
- Janssens, Gladys N.
- van der Hoeven, Nina W.
- Jewbali, Lucia S. D.
- Dubois, Eric A.
- Meuwissen, Martijn
- Rijpstra, Tom A.
- Bosker, Hans A.
- Blans, Michiel J.
- Bleeker, Gabe B.
- Baak, Remon
- Vlachojannis, Georgios J.
- Eikemans, Bob J. W.
- van der Harst, Pim
- van der Horst, Iwan C. C.
- Voskuil, Michiel
- van der Heijden, Joris J.
- Beishuizen, Albertus
- Stoel, Martin
- Camaro, Cyril
- van der Hoeven, Hans
- Henriques, Jose P.
- Vlaar, Alexander P. J.
- Vink, Maarten A.
- van den Bogaard, Bas
- Heestermans, Ton A. C. M.
- de Ruijter, Wouter
- Delnoij, Thijs S. R.
- Crijns, Harry J. G. M.
- Jessurun, Gillian A. J.
- Oemrawsingh, Pranobe V.
- Gosselink, Marcel T. M.
- Plomp, Koos
- Magro, Michael
- Elbers, Paul W. G.
- van de Ven, Peter M.
- van Loon, Ramon B.
- van Royen, Niels
DOIAbstract
Background: The effect of immediate coronary angiography and percutaneous coronary intervention (PCI) in patients who are successfully resuscitated after cardiac arrest in the absence of ST-segment elevation myocardial infarction (STEMI) on left ventricular function is currently unknown.Methods: This prespecified sub-study of a multicentre trial evaluated 552 patients, successfully resuscitated from out-of-hospital cardiac arrest without signs of STEMI. Patients were randomized to either undergo immediate coronary angiography or delayed coronary angiography, after neurologic recovery. All patients underwent PCI if indicated. The main outcomes of this analysis were left ventricular ejection fraction and end-diastolic and systolic volumes ass...
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