Bedaquiline and Delamanid Combination Treatment of 5 Patients with Pulmonary Extensively Drug-Resistant Tuberculosis
- Maryandyshev, Andrey
- Pontali, Emanuele
- Tiberi, Simon
- Akkerman, Onno
- Ganatra, Shashank
- Sadutshang, Tsetan Dorji
- Alffenaar, Jan-Willem
- Amale, Rohit
- Mullerpattan, Jai
- Topgyal, Sonam
- Udwadia, Zarir Farokh
- Centis, Rosella
- D'Ambrosio, Lia
- Sotgiu, Giovanni
- Migliori, Giovanni Battista
DOIAbstract
We report the experiences of 5 patients taking bedaquiline with delamanid in combination: 1 patient was cured; 3 culture converted, with 2 continuing and 1 changing therapy; and 1 died from respiratory insufficiency. For 2 patients, QT-interval prolongation but no arrhythmias occurred. Use of this therapy is justified for patients with limited options.</p
Add to ORKG