Many genotoxic chemotherapies have debilitating side effects and induce cellular senescence in normal tissues. Senescent cells acquire a pro-inflammatory phenotype which contributes to local and systemic inflammation. Eliminating senescent cells reduce several short- and long-term effects of the drugs, providing a new target to reduce the toxicity of anticancer treatments.</p
Cellular senescence is a permanent state of cell cycle arrest that promotes tissue remodeling during...
Cellular senescence is a typical tumor‐suppressive mechanism that restricts the proliferation of pre...
Cellular senescence is a state of stable cell cycle arrest that occurs in response to persistent cel...
Many genotoxic chemotherapies have debilitating side effects and induce cellular senescence in norma...
Cellular senescence is a complex process and is one of the key elements of ageing [...].</p
Several cancer interventions induce DNA damage and promote senescence in cancer and nonmalignant cel...
Cellular senescence is a state of stable, terminal cell cycle arrest associated with various macromo...
Cellular senescence represents a double-edged sword in cancer and its therapy. On one side, senescen...
Organismal aging is a multifactorial process characterized by the onset of degenerative conditions a...
Many genotoxic chemotherapies have debilitating side effects and induce cellular senescence in norma...
Cellular senescence suppresses cancer by irreversibly arresting cell proliferation. Senescent cells ...
Cellular senescence is a permanent state of cell cycle arrest that promotes tissue remodeling during...
Cellular senescence is a typical tumor‐suppressive mechanism that restricts the proliferation of pre...
Cellular senescence is a state of stable cell cycle arrest that occurs in response to persistent cel...
Many genotoxic chemotherapies have debilitating side effects and induce cellular senescence in norma...
Cellular senescence is a complex process and is one of the key elements of ageing [...].</p
Several cancer interventions induce DNA damage and promote senescence in cancer and nonmalignant cel...
Cellular senescence is a state of stable, terminal cell cycle arrest associated with various macromo...
Cellular senescence represents a double-edged sword in cancer and its therapy. On one side, senescen...
Organismal aging is a multifactorial process characterized by the onset of degenerative conditions a...
Many genotoxic chemotherapies have debilitating side effects and induce cellular senescence in norma...
Cellular senescence suppresses cancer by irreversibly arresting cell proliferation. Senescent cells ...
Cellular senescence is a permanent state of cell cycle arrest that promotes tissue remodeling during...
Cellular senescence is a typical tumor‐suppressive mechanism that restricts the proliferation of pre...
Cellular senescence is a state of stable cell cycle arrest that occurs in response to persistent cel...
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