The invention relates to novel pharmaceutically-useful peptides, in particular cyclic peptides that are agonists of the AngII type 2 receptor (AT2 receptor). The invention further relates to the use of such peptides as mecicaments, to pharmaceutical compositions containing them, and to their production
Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from a binding si...
The peptide hormone, angiotensin II, acts primarily via type I (AT1) and type II (AT2) angiotensin r...
The renin-angiotensin-aldosterone-system (RAAS) control blood-pressure regulation, exerted by the ma...
The invention relates to novel pharmaceutically-useful peptides, in particular cyclic peptides that ...
The invention relates to novel pharmaceutically-useful peptides, in particular cyclic peptides that ...
The G protein-coupled receptors (GPCRs) are important targets in drug discovery. In several cases, t...
We synthesized a molecule composed of two angiotensin II 4-8 pentapeptide fragments attached to a ca...
We synthesized a molecule composed of two angiotensin II 4-8 pentapeptide fragments attached to a ca...
Important information on the bioactive conformation of biologically active peptides may be obtained ...
We synthesized a molecule composed of two angiotensin II 4-8 pentapeptide fragments attached to a ca...
In the past decade a great deal of structural information for class A-GPCRs (G protein-coupled recep...
In the past decade a great deal of structural information for class A-GPCRs (G protein-coupled recep...
The angiotensin II (Ang II) type 1 and type 2 receptors (AT1R and AT2R) orchestrate an array of biol...
Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from a binding si...
Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from a binding si...
Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from a binding si...
The peptide hormone, angiotensin II, acts primarily via type I (AT1) and type II (AT2) angiotensin r...
The renin-angiotensin-aldosterone-system (RAAS) control blood-pressure regulation, exerted by the ma...
The invention relates to novel pharmaceutically-useful peptides, in particular cyclic peptides that ...
The invention relates to novel pharmaceutically-useful peptides, in particular cyclic peptides that ...
The G protein-coupled receptors (GPCRs) are important targets in drug discovery. In several cases, t...
We synthesized a molecule composed of two angiotensin II 4-8 pentapeptide fragments attached to a ca...
We synthesized a molecule composed of two angiotensin II 4-8 pentapeptide fragments attached to a ca...
Important information on the bioactive conformation of biologically active peptides may be obtained ...
We synthesized a molecule composed of two angiotensin II 4-8 pentapeptide fragments attached to a ca...
In the past decade a great deal of structural information for class A-GPCRs (G protein-coupled recep...
In the past decade a great deal of structural information for class A-GPCRs (G protein-coupled recep...
The angiotensin II (Ang II) type 1 and type 2 receptors (AT1R and AT2R) orchestrate an array of biol...
Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from a binding si...
Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from a binding si...
Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from a binding si...
The peptide hormone, angiotensin II, acts primarily via type I (AT1) and type II (AT2) angiotensin r...
The renin-angiotensin-aldosterone-system (RAAS) control blood-pressure regulation, exerted by the ma...