Linear dextrin (amylodextrin) and its soluble fraction were investigated for their suitability to enhance diazepam release from capsules and tablets. Drug release was analyzed in the USP XXI paddle apparatus and performed in phosphate buffer pH 6.8, with and without alpha-amylase, and in 0.1 N HCl solution. Diazepam release from capsules was slightly increased on application of amylodextrin, either as a filler in a physical mixture or as a carrier for solid dispersion of the drug, as compared to the release from capsules containing drug only. The limited increase in drug dissolution is caused by the limited solubility of amylodextrin. Application of the soluble fraction of amylodextrin therefore showed faster drug release. In contrast, the ...
Amylodextrin, metastable amylodextrins, Amylose V and metastable amylose were investigated on their ...
Moisture influences the consolidation behaviour of amylodextrin powders and the porosity and mechani...
Dextrans are a class of carbohydrate polymers extensively applied in pharmaceutical applications, pa...
Linear dextrin (amylodextrin) and its soluble fraction were investigated for their suitability to en...
This study reports the successful application of amylodextrin as a unique excipient in the design of...
Drug release from fatty suppository bases containing a solid dispersion of diazepam with amylodextri...
The ability of amylodextrin (a linear dextrin) to act as a complexing agent or as a carrier for soli...
Amylodextrin is a linear dextrin and can be produced by enzymatic hydrolysis of the alpha-1,6 glycos...
The linear dextrin amylodextrin was prepared by enzymatic hydrolysis from waxy maize. Four metastabl...
The complexation of both n-butyl-4-aminobenzoate and diazepam with dimethyl-beta-cyclodextrin and hy...
The complexation of both n-butyl-4-aminobenzoate and diazepam with dimethyl-beta-cyclodextrin and hy...
Amylodextrin is a suitable excipient for the design of solid controlled-release systems. The release...
Amylodextrin, metastable amylodextrins, Amylose V and metastable amylose were investigated on their ...
Moisture influences the consolidation behaviour of amylodextrin powders and the porosity and mechani...
Dextrans are a class of carbohydrate polymers extensively applied in pharmaceutical applications, pa...
Linear dextrin (amylodextrin) and its soluble fraction were investigated for their suitability to en...
This study reports the successful application of amylodextrin as a unique excipient in the design of...
Drug release from fatty suppository bases containing a solid dispersion of diazepam with amylodextri...
The ability of amylodextrin (a linear dextrin) to act as a complexing agent or as a carrier for soli...
Amylodextrin is a linear dextrin and can be produced by enzymatic hydrolysis of the alpha-1,6 glycos...
The linear dextrin amylodextrin was prepared by enzymatic hydrolysis from waxy maize. Four metastabl...
The complexation of both n-butyl-4-aminobenzoate and diazepam with dimethyl-beta-cyclodextrin and hy...
The complexation of both n-butyl-4-aminobenzoate and diazepam with dimethyl-beta-cyclodextrin and hy...
Amylodextrin is a suitable excipient for the design of solid controlled-release systems. The release...
Amylodextrin, metastable amylodextrins, Amylose V and metastable amylose were investigated on their ...
Moisture influences the consolidation behaviour of amylodextrin powders and the porosity and mechani...
Dextrans are a class of carbohydrate polymers extensively applied in pharmaceutical applications, pa...