Add to ORKGThe objective of this paper is to present an update of mechanisms responsible for drug resistance in ovarian cancer and the possible therapeutic options to modulate this resistance using literature review with emphasis on data acquired in studies comprising ovarian tumor samples.The classic concepts on resistance in ovarian cancer, namely platinum and multidrug resistance, are briefly discussed, followed by a description of more recent insights concerning the role of apoptosis in the development of chemoresistance.A wide variety of mechanisms may be responsible for drug resistance in ovarian cancer. However, a growing body of evidence indicates that defects in the intra- and extracellular apoptotic pathways are an important cause of resista...
Despite the initially high response rate to standard front-line debulking surgery followed by platin...
Abstract Ovarian cancer is among the most lethal of all malignancies in women. While c...
Ovarian cancer represents the fifth most frequent cause of death as a result of malignant processes ...
The objective of this paper is to present an update of mechanisms responsible for drug resistance in...
The cancer that originates in ovary is one of the most deadly gynecological malignancies. Despite ad...
Ovarian cancer is one of the most lethal gynecologic cancers. The standard therapy for ovarian cance...
SummaryChemotherapy is a major treatment modality for ovarian cancer, but chemoresistance is a clini...
Background: Both intrinsic and acquired drug resistance occur in ovarian cancer. Much work on in viv...
The aim of the study is to review the mechanisms of resistance to four classes of drugs that are wid...
Ovarian cancer is the fifth most common cancer affecting women and the most lethal cancer among the ...
In the United States, over 100,000 women are diagnosed with a gynecologic malignancy every year, wit...
Ovarian carcinoma is the most lethal gynaecologic malignancy. Despite wide initial sensibility to ch...
Ovarian cancer is the fifth leading cause of cancer death among women and the most lethal gynecologi...
High-grade serous ovarian cancer (HGSOC) is one of the deadliest cancers for women. The standard car...
Drug resistance to alkylating agents is known to be a major clinical problem in the management of pa...
Despite the initially high response rate to standard front-line debulking surgery followed by platin...
Abstract Ovarian cancer is among the most lethal of all malignancies in women. While c...
Ovarian cancer represents the fifth most frequent cause of death as a result of malignant processes ...
The objective of this paper is to present an update of mechanisms responsible for drug resistance in...
The cancer that originates in ovary is one of the most deadly gynecological malignancies. Despite ad...
Ovarian cancer is one of the most lethal gynecologic cancers. The standard therapy for ovarian cance...
SummaryChemotherapy is a major treatment modality for ovarian cancer, but chemoresistance is a clini...
Background: Both intrinsic and acquired drug resistance occur in ovarian cancer. Much work on in viv...
The aim of the study is to review the mechanisms of resistance to four classes of drugs that are wid...
Ovarian cancer is the fifth most common cancer affecting women and the most lethal cancer among the ...
In the United States, over 100,000 women are diagnosed with a gynecologic malignancy every year, wit...
Ovarian carcinoma is the most lethal gynaecologic malignancy. Despite wide initial sensibility to ch...
Ovarian cancer is the fifth leading cause of cancer death among women and the most lethal gynecologi...
High-grade serous ovarian cancer (HGSOC) is one of the deadliest cancers for women. The standard car...
Drug resistance to alkylating agents is known to be a major clinical problem in the management of pa...
Despite the initially high response rate to standard front-line debulking surgery followed by platin...
Abstract Ovarian cancer is among the most lethal of all malignancies in women. While c...
Ovarian cancer represents the fifth most frequent cause of death as a result of malignant processes ...