Regulation of the metabolism of methanol, dihydroxyacetone and glycerol in the yeast Hansenula polymorpha.

ln recent years there has been an increasing interest in the possible application of microorganisms for the production of fine chemicals. [...] This thesis reports the results of studies in which various physiological and biochemical aspects of dihydroryacetone (DHA) and glycerol synthesis and utilization by the methylotrophic yeast Hansenula polymorpha were investigated. The results provide further iasight into the regulation of methanol, DHA, and glycerol metabolism in this yeast, and a firm basis for further studies aiming to optimize strain properties and physiological conditions for DFIA production up to industrially interesting levels. ... Zie: Summar