Add to ORKGRecent knowledge on apoptosis has made it possible to devise novel approaches, which exploit this process to treat cancer. In this review, we discuss in detail approaches to induce tumor cell apoptosis, their mechanism of action, stage of development, and possible drawbacks. Finally, the obstacles yet to be overcome and the perspectives for potential clinical use of apoptosis-triggering approaches in cancer therapy in the future are assessed.</p
Apoptosis plays a centrale role in regulating tissue homeostasis. The balance between cell death and...
Apoptosis is a tightly regulated cell suicide program that plays an essential role in the maintenanc...
Apoptosis is a form of programmed cell death that results in the orderly and efficient removal of da...
Recent knowledge on apoptosis has made it possible to devise novel approaches, which exploit this pr...
Apoptosis is a ubiquitous, highly coordinated process of self-destruction. Conventional cancer thera...
Defects in apoptosis, a complex cell death program that controls tissue homeostasis, play important ...
Apoptosis is a ubiquitous, highly coordinated process of self-destruction. Conventional cancer thera...
Important breakthroughs in cancer therapy include clinical application of antibodies, such as Rituxi...
Important breakthroughs in cancer therapy include clinical application of antibodies, such as Rituxi...
Apoptosis plays a crucial role in the normal development, homeostasis of multicellular organisms, ca...
This review outlines the principal limitations of the mechanisms of active cell death (ACD, apoptosi...
Apoptosis (programmed cell death) research has received much attention because of its wide-ranging i...
The induction of apoptosis, a highly regulated and clearly defined mode of cell dying, is a vital te...
The observation that tumor development frequently is accompanied by apoptotic defects and the meanwh...
Cancer is one of the most important causes of death in our era. Multifactorial causes are involved i...
Apoptosis plays a centrale role in regulating tissue homeostasis. The balance between cell death and...
Apoptosis is a tightly regulated cell suicide program that plays an essential role in the maintenanc...
Apoptosis is a form of programmed cell death that results in the orderly and efficient removal of da...
Recent knowledge on apoptosis has made it possible to devise novel approaches, which exploit this pr...
Apoptosis is a ubiquitous, highly coordinated process of self-destruction. Conventional cancer thera...
Defects in apoptosis, a complex cell death program that controls tissue homeostasis, play important ...
Apoptosis is a ubiquitous, highly coordinated process of self-destruction. Conventional cancer thera...
Important breakthroughs in cancer therapy include clinical application of antibodies, such as Rituxi...
Important breakthroughs in cancer therapy include clinical application of antibodies, such as Rituxi...
Apoptosis plays a crucial role in the normal development, homeostasis of multicellular organisms, ca...
This review outlines the principal limitations of the mechanisms of active cell death (ACD, apoptosi...
Apoptosis (programmed cell death) research has received much attention because of its wide-ranging i...
The induction of apoptosis, a highly regulated and clearly defined mode of cell dying, is a vital te...
The observation that tumor development frequently is accompanied by apoptotic defects and the meanwh...
Cancer is one of the most important causes of death in our era. Multifactorial causes are involved i...
Apoptosis plays a centrale role in regulating tissue homeostasis. The balance between cell death and...
Apoptosis is a tightly regulated cell suicide program that plays an essential role in the maintenanc...
Apoptosis is a form of programmed cell death that results in the orderly and efficient removal of da...