The initial cytogenetic analysis of a biphasic synovial sarcoma revealed complex anomalies involving six different chromosomes: 46,Y,t(X;18;5;4)(p11;q11;p13;q12),t(2;5)(q35;q11). After fluorescence in situ hybridization (FISH) analysis, using chromosome X-specific plasmid library and YAC probes, the situation appeared to be even more complex, with an insertion of part of the X chromosome short arm into the der(5)t(5;18). In spite of these complex chromosomal rearrangements, the Xp11 breakpoint could be mapped to within the ornithine aminotransferase (OAT)L1 cluster, very similar to that reported previously for the standard t(X;18)(p11;q11) in synovial sarcomas. These findings suggest common pathogenetic pathways in these cytogenetically dif...
Recent studies have identified a specific chromosomal translocation, t(X;18)(p11.2;q11.2), in a high...
A high proportion of synovial sarcomas contain a chromosome translocation t(X;18)(p11.2;q11.2). We h...
Human synovial sarcomas contain a recurrent and specific chromosomal translocation t(X;18)(p11.2;q11...
The initial cytogenetic analysis of a biphasic synovial sarcoma revealed complex anomalies involving...
The initial cytogenetic analysis of a biphasic synovial sarcoma revealed complex anomalies involving...
In a previous study we localized the synovial sarcoma-associated t(X;18)(p11;q11) breakpoint within ...
A high proportion of synovial sarcomas contain the reciprocal translocation t(X;18)(p11.2;q11.2). We...
A high proportion of synovial sarcomas contain the reciprocal translocation t(X;18)(p11.2;q11.2). We...
Fluorescence in situ hybridization (FISH) and molecular analyses of synovial sarcomas with cytogenet...
Synovial sarcomas are soft tissue tumors that occur mainly in adolescents and young adults. The chro...
Cytogenetic study of five biphasic and five monophasic synovial sarcomas revealed the specific abnor...
Cytogenetic analysis of a metastatic biphasic synovial sarcoma showed two structural abnormalities: ...
A somatic cell hybrid containing the synovial sarcoma-associated t(X;18)(p11.2;q11.2) derivative (de...
A somatic cell hybrid containing the synovial sarcoma-associated t(X;18)(p11.2;q11.2) derivative (de...
Synovial sarcomas are high-grade malignant mesenchymal tumors that account for 10% of all soft-tissu...
Recent studies have identified a specific chromosomal translocation, t(X;18)(p11.2;q11.2), in a high...
A high proportion of synovial sarcomas contain a chromosome translocation t(X;18)(p11.2;q11.2). We h...
Human synovial sarcomas contain a recurrent and specific chromosomal translocation t(X;18)(p11.2;q11...
The initial cytogenetic analysis of a biphasic synovial sarcoma revealed complex anomalies involving...
The initial cytogenetic analysis of a biphasic synovial sarcoma revealed complex anomalies involving...
In a previous study we localized the synovial sarcoma-associated t(X;18)(p11;q11) breakpoint within ...
A high proportion of synovial sarcomas contain the reciprocal translocation t(X;18)(p11.2;q11.2). We...
A high proportion of synovial sarcomas contain the reciprocal translocation t(X;18)(p11.2;q11.2). We...
Fluorescence in situ hybridization (FISH) and molecular analyses of synovial sarcomas with cytogenet...
Synovial sarcomas are soft tissue tumors that occur mainly in adolescents and young adults. The chro...
Cytogenetic study of five biphasic and five monophasic synovial sarcomas revealed the specific abnor...
Cytogenetic analysis of a metastatic biphasic synovial sarcoma showed two structural abnormalities: ...
A somatic cell hybrid containing the synovial sarcoma-associated t(X;18)(p11.2;q11.2) derivative (de...
A somatic cell hybrid containing the synovial sarcoma-associated t(X;18)(p11.2;q11.2) derivative (de...
Synovial sarcomas are high-grade malignant mesenchymal tumors that account for 10% of all soft-tissu...
Recent studies have identified a specific chromosomal translocation, t(X;18)(p11.2;q11.2), in a high...
A high proportion of synovial sarcomas contain a chromosome translocation t(X;18)(p11.2;q11.2). We h...
Human synovial sarcomas contain a recurrent and specific chromosomal translocation t(X;18)(p11.2;q11...