Add to ORKGThe enzymatic hydrolyses of a variety of alpha-substituted mandelic and lactic esters using pig liver esterase (PLE) have been investigated. High to moderate enantioselectivity was found for various alpha-substituted mandelic esters, whereas PLE showed low to no enantioselectivity for alpha-substituted lactic esters. We observed that the enantioselectivity of PLE depends strongly on the length and nature of the substituent at the alpha-position. Some consequences for an active site model of PLE are discussed.</p
A practical mass spectrometry-based enantioselectivity assay is presented which makes use of enantio...
N,O-Diacetyl-2-amino-1-arylethanol can be efficiently resolved by horse liver esterase (HLE). A rema...
Desymmetrization of dimethyl meso-piperidine-3,5-dicarboxylates 3a-c with pig liver esterase (PLE), ...
The enzymatic hydrolyses of a variety of alpha-substituted mandelic and lactic esters using pig live...
Six pigs in a pot: Pig liver esterase (PLE) is among the most widely studied esterase enzymes utiliz...
Prochiral diester malonates have been hydrolyzed in the presence of Pig Liver Esterase (PLE). Severa...
Pig Liver Esterase (PLE) is a serine protease enzyme that can interact with one side of a diester to...
Previously, we have reported the effect of several co-solvents, including ethanol, on the enantiosel...
Saturated methyl ester is preferentially hydrolysed in presence of corresponding α,β-unsaturated est...
Abstract: In order to gain a more detailed insight into the relationship between substrate structure...
Preparation of optically-pure derivatives of 2-hydroxy-2-(3-hydroxyphenyl)-2-phenylacetic acid of ge...
Pig liver Esterase (PLE) and Pig Pancreas Lipase (PPL) catalysed hydrolysis of (± ) trans-3-carbetho...
974-980The regio and stereoselectivity of PLE and PPL-catalyzed hydrolysis of a number of conformat...
Pig liver esterase (PLE, EC 3.1.1.1) has been employed extensively for research purposes during the ...
Lipases and Esterases can be used as efficient biocatalysts for the preparation of a wide variety of...
A practical mass spectrometry-based enantioselectivity assay is presented which makes use of enantio...
N,O-Diacetyl-2-amino-1-arylethanol can be efficiently resolved by horse liver esterase (HLE). A rema...
Desymmetrization of dimethyl meso-piperidine-3,5-dicarboxylates 3a-c with pig liver esterase (PLE), ...
The enzymatic hydrolyses of a variety of alpha-substituted mandelic and lactic esters using pig live...
Six pigs in a pot: Pig liver esterase (PLE) is among the most widely studied esterase enzymes utiliz...
Prochiral diester malonates have been hydrolyzed in the presence of Pig Liver Esterase (PLE). Severa...
Pig Liver Esterase (PLE) is a serine protease enzyme that can interact with one side of a diester to...
Previously, we have reported the effect of several co-solvents, including ethanol, on the enantiosel...
Saturated methyl ester is preferentially hydrolysed in presence of corresponding α,β-unsaturated est...
Abstract: In order to gain a more detailed insight into the relationship between substrate structure...
Preparation of optically-pure derivatives of 2-hydroxy-2-(3-hydroxyphenyl)-2-phenylacetic acid of ge...
Pig liver Esterase (PLE) and Pig Pancreas Lipase (PPL) catalysed hydrolysis of (± ) trans-3-carbetho...
974-980The regio and stereoselectivity of PLE and PPL-catalyzed hydrolysis of a number of conformat...
Pig liver esterase (PLE, EC 3.1.1.1) has been employed extensively for research purposes during the ...
Lipases and Esterases can be used as efficient biocatalysts for the preparation of a wide variety of...
A practical mass spectrometry-based enantioselectivity assay is presented which makes use of enantio...
N,O-Diacetyl-2-amino-1-arylethanol can be efficiently resolved by horse liver esterase (HLE). A rema...
Desymmetrization of dimethyl meso-piperidine-3,5-dicarboxylates 3a-c with pig liver esterase (PLE), ...