The aim of this study was to develop a user-friendly model for spray drying that can aid in the development of a pharmaceutical product, by shifting from a trial-and-error towards a quality-by-design approach. To achieve this, a spray dryer model was developed in commercial and open source spreadsheet software. The output of the model was first fitted to the experimental output of a Büchi B-290 spray dryer and subsequently validated. The predicted outlet temperatures of the spray dryer model matched the experimental values very well over the entire range of spray dryer settings that were tested. Finally, the model was applied to produce glassy sugars by spray drying, an often used excipient in formulations of biopharmaceuticals. For the pro...
Spray dried vaccine formulations might be an alternative to traditional lyophilized vaccines. Compar...
Tese de doutoramento, Farmácia (Tecnologia Farmacêutica), Universidade de Lisboa, Faculdade de Farmá...
Spray dried vaccine formulations might be an alternative to traditional lyophilized vaccines. Compar...
The aim of this study was to develop a user-friendly model for spray drying that can aid in the deve...
The aim of this study was to develop a user-friendly model for spray drying that can aid in the deve...
The aim of this study was to develop a user-friendly model for spray drying that can aid in the deve...
<div><p>The aim of this study was to develop a user-friendly model for spray drying that can aid in ...
The aim of this study was to develop a user-friendly model for spray drying that can aid in the deve...
The aim of this study was to develop a user-friendly model for spray drying that can aid in the deve...
Abstract Solid amorphous dispersions are frequently used to improve the solubility and, thus, the bi...
The main purpose of spray drying method in pharmaceutical technology is to get dried particles in de...
Spray drying is a well-known method of particle production which comprises the transformation of a f...
INTRODUCTION: The rising demand for pharmaceutical particles with tailored physicochemical propertie...
INTRODUCTION: The rising demand for pharmaceutical particles with tailored physicochemical propertie...
INTRODUCTION: The rising demand for pharmaceutical particles with tailored physicochemical propertie...
Spray dried vaccine formulations might be an alternative to traditional lyophilized vaccines. Compar...
Tese de doutoramento, Farmácia (Tecnologia Farmacêutica), Universidade de Lisboa, Faculdade de Farmá...
Spray dried vaccine formulations might be an alternative to traditional lyophilized vaccines. Compar...
The aim of this study was to develop a user-friendly model for spray drying that can aid in the deve...
The aim of this study was to develop a user-friendly model for spray drying that can aid in the deve...
The aim of this study was to develop a user-friendly model for spray drying that can aid in the deve...
<div><p>The aim of this study was to develop a user-friendly model for spray drying that can aid in ...
The aim of this study was to develop a user-friendly model for spray drying that can aid in the deve...
The aim of this study was to develop a user-friendly model for spray drying that can aid in the deve...
Abstract Solid amorphous dispersions are frequently used to improve the solubility and, thus, the bi...
The main purpose of spray drying method in pharmaceutical technology is to get dried particles in de...
Spray drying is a well-known method of particle production which comprises the transformation of a f...
INTRODUCTION: The rising demand for pharmaceutical particles with tailored physicochemical propertie...
INTRODUCTION: The rising demand for pharmaceutical particles with tailored physicochemical propertie...
INTRODUCTION: The rising demand for pharmaceutical particles with tailored physicochemical propertie...
Spray dried vaccine formulations might be an alternative to traditional lyophilized vaccines. Compar...
Tese de doutoramento, Farmácia (Tecnologia Farmacêutica), Universidade de Lisboa, Faculdade de Farmá...
Spray dried vaccine formulations might be an alternative to traditional lyophilized vaccines. Compar...