Influenza vaccines have been in use for more than 60 years and have proven to be efficacious in protecting from influenza infections during epidemics and the recent H1N1 pandemic. The development of influenza vaccines has so far been largely based on empirical grounds, which leaves room for vaccine improvement by implementation of recent insights in innate and adaptive immunity. Also, evaluation and approval of new vaccines rely on rather broad correlates of protection such as the hemagglutination inhibition titre, thereby neglecting qualitative aspects of the immune response. Here we discuss how current inactivated influenza vaccine formulations differ in the type of immune response they elcit, their protective capacity, and what causes th...
Influenza remains one of the most serious viral diseases in the world, causing substantial morbidity...
Vaccination against influenza is the most effective approach for reducing influenza morbidity and mo...
The alarming rise of morbidity and mortality caused by influenza pandemics and epidemics has drawn a...
Influenza vaccines have been in use for more than 60 years and have proven to be efficacious in prot...
Influenza vaccines have been in use for more than 60 years and have proven to be efficacious in prot...
Despite the widespread use of seasonal influenza vaccines, there is urgent need for a universal infl...
Despite seasonal influenza vaccines having been routinely used for many decades, influenza A virus c...
Despite the widespread availability and use of influenza vaccines, influenza still poses a considera...
Influenza is a major respiratory pathogen causing annual outbreaks and occasional pandemics. Influen...
The licensed seasonal influenza vaccines predominantly induce neutralizing antibodies against immuno...
Despite the widespread availability and use of influenza vaccines, influenza still poses a considera...
Influenza is a very contagious disease that causes serious illness and death every year. Antigenic d...
For centuries, the development of vaccines to prevent infectious disease was an empirical process. F...
The emergence of avian influenza A/H5N1 viruses that can cross the species barrier and that cause of...
Influenza viruses have affected the world for over a century, causing multiple pandemics. Throughout...
Influenza remains one of the most serious viral diseases in the world, causing substantial morbidity...
Vaccination against influenza is the most effective approach for reducing influenza morbidity and mo...
The alarming rise of morbidity and mortality caused by influenza pandemics and epidemics has drawn a...
Influenza vaccines have been in use for more than 60 years and have proven to be efficacious in prot...
Influenza vaccines have been in use for more than 60 years and have proven to be efficacious in prot...
Despite the widespread use of seasonal influenza vaccines, there is urgent need for a universal infl...
Despite seasonal influenza vaccines having been routinely used for many decades, influenza A virus c...
Despite the widespread availability and use of influenza vaccines, influenza still poses a considera...
Influenza is a major respiratory pathogen causing annual outbreaks and occasional pandemics. Influen...
The licensed seasonal influenza vaccines predominantly induce neutralizing antibodies against immuno...
Despite the widespread availability and use of influenza vaccines, influenza still poses a considera...
Influenza is a very contagious disease that causes serious illness and death every year. Antigenic d...
For centuries, the development of vaccines to prevent infectious disease was an empirical process. F...
The emergence of avian influenza A/H5N1 viruses that can cross the species barrier and that cause of...
Influenza viruses have affected the world for over a century, causing multiple pandemics. Throughout...
Influenza remains one of the most serious viral diseases in the world, causing substantial morbidity...
Vaccination against influenza is the most effective approach for reducing influenza morbidity and mo...
The alarming rise of morbidity and mortality caused by influenza pandemics and epidemics has drawn a...