Tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) directly influence thrombus formation and degradation, and have been identified as risk factors for thromboembolic disease. Prior studies investigated determinants of t-PA and PAI-1 expression, but mainly in Caucasian subjects. The aim of this study was to identify the contributions of genetic and other factors to inter-individual variation in plasma levels of t-PA and PAI-1 in a large-scale population-based sample from urban West Africa. t-PA, PAI-1 and several demographic, anthropometric, and metabolic parameters were measured in 992 residents of Sunyani, the capital of the Brong-Ahafo region of Ghana. In addition, nine gene polymorphisms associated wit...
Important biochemical constituents of the fibrinolytic system include tissue-type plasminogen activa...
AbstractTissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) directly i...
Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) directly influence...
Tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) directly infl...
Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor I (PAI-I) directly influence...
<div><p>Plasminogen activator inhibitor 1 (PAI-1), a major modulator of the fibrinolytic system, is ...
bosis has a significant genetic component that is partly due to the expression of two proteins, tiss...
Plasminogen activator inhibitor 1 (PAI-1), a major modulator of the fibrinolytic system, is an impor...
Thrombosis is a key factor in the pathophysiology of cardiovascular disease. Important biochemical c...
Background-Metabolic syndrome (MetS) is diagnosed by the presence of at least 3 of the following: ob...
The proteins, tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1), act...
Important biochemical constituents of the fibrinolytic system include tissue-type plasminogen activa...
AbstractTissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) directly i...
Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) directly influence...
Tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) directly infl...
Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor I (PAI-I) directly influence...
<div><p>Plasminogen activator inhibitor 1 (PAI-1), a major modulator of the fibrinolytic system, is ...
bosis has a significant genetic component that is partly due to the expression of two proteins, tiss...
Plasminogen activator inhibitor 1 (PAI-1), a major modulator of the fibrinolytic system, is an impor...
Thrombosis is a key factor in the pathophysiology of cardiovascular disease. Important biochemical c...
Background-Metabolic syndrome (MetS) is diagnosed by the presence of at least 3 of the following: ob...
The proteins, tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1), act...
Important biochemical constituents of the fibrinolytic system include tissue-type plasminogen activa...
AbstractTissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) directly i...
Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) directly influence...