Patients with heart failure have, in spite of improved palliative therapies, bad prognosis. Cardiac tissue engineering by use of a temporary bioscaffold and cardiomyocytes may help to find answers for future treatments in heart failure. For that purpose two neonatal rat heart ventricular cell fractions were obtained after a gradient cell separation. Time related characteristics of Fractions I and 11 were established in two-dimensional (2-D) and three-dimensional (3-D) cell cultures. The 3-D cardiac constructs were obtained by use of a bovine type I collagen matrix after culturing either under static conditions or in the HARV bioreactor. With the 2-D cultures contracting cells were present after 1 day, and reached confluency from day 5 on an...
Engineered cardiac tissue models become increasingly important for understanding normal and diseased...
Heart disease is the leading cause of death in many developing and industrialized countries. The los...
Heart disease is the leading cause of death in many developing and industrialized countries. The los...
Patients with heart failure have, in spite of improved palliative therapies, bad prognosis. Cardiac ...
Patients with heart failure have, in spite of improved palliative therapies, bad prognosis. Cardiac ...
Implantation of engineered cardiac tissue may restore lost cardiac function to damaged myocardium. W...
Implantation of engineered cardiac tissue may restore lost cardiac function to damaged myocardium. W...
Engineering cardiac tissue without the mechanical restriction of scaffolds has many important scient...
Engineered cardiac tissue models become increasingly important for understanding normal and diseased...
Engineered cardiac tissue models become increasingly important for understanding normal and diseased...
Engineered cardiac tissue models become increasingly important for understanding normal and diseased...
Cardiac myocytes and fibroblasts are essential elements of myocardial tissue structure and function....
Cardiac myocytes and fibroblasts are essential elements of myocardial tissue structure and function....
Heart disease is the leading cause of death in many developing and industrialized countries. The los...
Engineering cardiac tissue in three dimensions is limited by the ability to supply nourishment to th...
Engineered cardiac tissue models become increasingly important for understanding normal and diseased...
Heart disease is the leading cause of death in many developing and industrialized countries. The los...
Heart disease is the leading cause of death in many developing and industrialized countries. The los...
Patients with heart failure have, in spite of improved palliative therapies, bad prognosis. Cardiac ...
Patients with heart failure have, in spite of improved palliative therapies, bad prognosis. Cardiac ...
Implantation of engineered cardiac tissue may restore lost cardiac function to damaged myocardium. W...
Implantation of engineered cardiac tissue may restore lost cardiac function to damaged myocardium. W...
Engineering cardiac tissue without the mechanical restriction of scaffolds has many important scient...
Engineered cardiac tissue models become increasingly important for understanding normal and diseased...
Engineered cardiac tissue models become increasingly important for understanding normal and diseased...
Engineered cardiac tissue models become increasingly important for understanding normal and diseased...
Cardiac myocytes and fibroblasts are essential elements of myocardial tissue structure and function....
Cardiac myocytes and fibroblasts are essential elements of myocardial tissue structure and function....
Heart disease is the leading cause of death in many developing and industrialized countries. The los...
Engineering cardiac tissue in three dimensions is limited by the ability to supply nourishment to th...
Engineered cardiac tissue models become increasingly important for understanding normal and diseased...
Heart disease is the leading cause of death in many developing and industrialized countries. The los...
Heart disease is the leading cause of death in many developing and industrialized countries. The los...