Towards optimalisation of mechanical reperfusion therapy for acute myocardial

This thesis adresses diverse aspects of daily clinical practice in a setting where all patients with accute myocardial infarction are treated with primary angioplasty. The importance of pre-hospital infarction-diagnosis and triage, the influence of pharmacological pre-treatment before primary angioplasty, the extent of platelet aggregation inhibition with different antiplatelet treatment regimens, the importance of initial patency of the infarct-related artery and the outcome after failure of mechanical reperfusion therapy are analysed. ... Zie: Summar