Add to ORKGComputer-aided drug design is among the most valuable tools we have in order to design new drug molecules. Herein, with the aid of the Drug Design Workshop platform, we describe our efforts to propose a new anti-inflammatory drug with a high selectivity upon the COX-2 target protein
56-63The energetics and models of COX-2 complexed with nonsteroidal anti-innammatory drugs (NSAIDs)...
The recent discovery of a second, inducible isoform of cyclooxygenase, COX-2, has stimulated the sea...
<div><p>Cyclooxygenase-2 (COX-2) plays an important role in memory consolidation and synaptic activi...
Cyclooxygenase-2 (COX-2) produces prostaglandins in inflamed tissues and hence has been considered a...
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used classes of drugs. T...
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used classes of drugs. T...
ABSTRACT: The key feature of inflammation is pain and it is mediated by molecules called prostaglan...
Computer-based drug design is increasingly used in strategies for discovering new molecules for ther...
Background: Inflammation is basically caused with conversion of Arachidonic acid into Prostaglandin ...
Objective: The aim of the present work was to design the novel series of chalcone derivatives of ind...
Cyclooxygenase (COX) is a key enzyme in the biosynthetic pathway leading to the formation of prostag...
L’inflammation est un phénomène affectant des millions de personnes à travers le monde. Il existe un...
Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are currently widely used as fever a...
In the field of molecular modeling, docking may be a method which predicts the well-liked orientatio...
Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are currently widely used as fever a...
56-63The energetics and models of COX-2 complexed with nonsteroidal anti-innammatory drugs (NSAIDs)...
The recent discovery of a second, inducible isoform of cyclooxygenase, COX-2, has stimulated the sea...
<div><p>Cyclooxygenase-2 (COX-2) plays an important role in memory consolidation and synaptic activi...
Cyclooxygenase-2 (COX-2) produces prostaglandins in inflamed tissues and hence has been considered a...
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used classes of drugs. T...
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used classes of drugs. T...
ABSTRACT: The key feature of inflammation is pain and it is mediated by molecules called prostaglan...
Computer-based drug design is increasingly used in strategies for discovering new molecules for ther...
Background: Inflammation is basically caused with conversion of Arachidonic acid into Prostaglandin ...
Objective: The aim of the present work was to design the novel series of chalcone derivatives of ind...
Cyclooxygenase (COX) is a key enzyme in the biosynthetic pathway leading to the formation of prostag...
L’inflammation est un phénomène affectant des millions de personnes à travers le monde. Il existe un...
Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are currently widely used as fever a...
In the field of molecular modeling, docking may be a method which predicts the well-liked orientatio...
Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are currently widely used as fever a...
56-63The energetics and models of COX-2 complexed with nonsteroidal anti-innammatory drugs (NSAIDs)...
The recent discovery of a second, inducible isoform of cyclooxygenase, COX-2, has stimulated the sea...
<div><p>Cyclooxygenase-2 (COX-2) plays an important role in memory consolidation and synaptic activi...