Proteomics to elucidate molecular mechanisms of atherosclerosis and calcific aortic valve disease

富山大学・富医薬博乙第85号・東 秀行・2022/03/02公開論文1.Higashi H, Maejima T, Lee LH, Yamazaki Y, Hottiger MO, Singh SA, Aikawa M. A Study into the ADP-Ribosylome of IFN-γ-Stimulated THP-1 Human Macrophage-like Cells Identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-Ribosylation. J Proteome Res. 2019 Apr 5;18(4):1607-1622. doi: 10.1021/acs.jproteome.8b00895. Epub 2019 Mar 21. 2.A Novel Spectral Annotation Strategy Streamlines Reporting of Mono-ADP-ribosylated Peptides Derived from Mouse Liver and Spleen in Response to IFN-γKuraoka, Shiori et al.Molecular & Cellular Proteomics, Volume 21, Issue 4, 1001533.Published December 22, 2020Citation Information: JCI Insight. 2021;6(3):e143526. https://doi.org/10.1172/jci.insight.143526.4.Schlotter F, Halu A, Goto S, Blaser MC, Body SC, Lee LH, Higashi H, DeLaughter DM, Hutcheson JD, Vyas P, Pham T, Rogers MA, Sharma A, Seidman CE, Loscalzo J, Seidman JG, Aikawa M, Singh SA, Aikawa E. Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease. Circulation. 2018 Jul 24;138(4):377-393. doi: 10.1161/CIRCULATIONAHA.117.032291.5.: Goto S, Rogers MA, Blaser MC, Higashi H, Lee LH, Schlotter F, Body SC, Aikawa M, Singh SA and Aikawa E (2019) Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification. Front. Cardiovasc. Med. 6:49. doi: 10.3389/fcvm.2019.00049富山大