Background: Neonatal abstinence syndrome (NAS), characterized by tremors, vomiting, diarrhea, fever, diaphoresis, irritability, high-pitched cry and tachypnea, affects some newborns with prenatal opioid exposure. In 2018, the rate of opioid use amongst Vermont’s pregnant women was reported highest in the nation, with a rate of infants developing NAS significantly higher than the national average. Purpose: This project assessedthe use and impact of evidence-based best practice when caring for infants with NAS in Vermont’s birth hospitals. These included utilization of the Eat, Sleep, Console model, non-pharmaceutical interventions, and volunteer cuddler programs. Methods: This project adopted a mixed method approach, using internet-based su...