The paper presents the experience in designing and manufacture of explosion chambers for researching purposes and technological applications gathered in Lavrentyev Institute of Hydrodynamics of Siberian Branch of Russian Academy of Sciences. The peculiarity of the developed explosion chambers is that they are all-metal units with a long service life (10 thousand explosions and more); they completely isolate blast effects (shock wave, seismic wave, etc.) and hence can be installed in laboratory rooms and industrial premises and, when necessary, can be disassembled and moved to a new place of exploitation. Presented examples illustrate the application of the explosion chambers in production of new materials, articles, and for elimination of a...