Low Power, High Dynamic Range Analogue Multiplexer for Multi-Channel Parallel Recording of Neuronal Signals Using Multi-Electrode Arrays

In the paper we present the design and test resultsof an integrated circuit combining a sample & hold circuit andan analogue multiplexer. The circuit has been designed as abuilding block for a multi-channel Application Specific IntegratedCircuit (ASIC) for recording signals from alive neuronal tissueusing high-density micro-electrode arrays (MEAs). The designis optimised with respect to critical requirements for suchapplications, i.e. short sampling time, low power dissipation, goodl inearity and high dynamic range. Presented design comprisessample&hold circuits with class AB operational amplifier, novelshift register, which allows minimising cross-coupling of the clocksignal and control logic. The circuit has been designed in 0.35µm CMOS process and has been successfully implemented in aprototype multi-channel ASIC