In the context of increased interest in permeability enhancement technologies to achieve mucosal delivery of drugs and biologics, we report our study on effects of the amphiphilic surfactant at cell membrane and cell population levels. Our results show that modulation in membrane order and fluidity initially occurs on insertion of individual surfactant molecules into the outer leaflet of membrane lipid bilayer; a process occurring at concentrations below surfactant's critical micellar concentration. The surfactant insertion, and consequent increase in membrane fluidity, are observed to be spatially heterogenous, i.e. manifested as ‘patches’ of increased membrane fluidity. At the cell population level, spatially heterogeneous activity of sur...
The stratum corneum (SC) is the ourtermost layer of the epidermis and has a brick-and-mortar-like st...
International audienceThe mechanism of surfactant-induced cell lysis has been studied with quantitat...
The mechanism of surfactant-induced cell lysis has been studied with quantitative coherent anti-Stok...
In the context of increased interest in permeability enhancement technologies to achieve mucosal del...
Surfactin, a bacterial amphiphilic lipopeptide is attracting more and more attention in view of its ...
Surfactin, a bacterial amphiphilic lipopeptide is attracting more and more attention in view of its ...
AbstractSurfactin, a bacterial amphiphilic lipopeptide is attracting more and more attention in view...
Amphipathic, non-ionic surfactants are widely used in pharmaceutical and food industries to enhance ...
The lipopeptide surfactin exhibits promising antimicrobial activities which are hampered by haemolyt...
This work aims at a better understanding of the parameters and properties of surfactants that govern...
AbstractWe propose classifying surfactants with respect to their effect on membrane order, which is ...
Surfactin is an antibiotic produced by several strains of B. subtilis. Its broad range of biological...
The use of surfactants as drug permeability enhancers across epithelial barriers remains a challenge...
The stratum corneum (SC) is the ourtermost layer of the epidermis and has a brick-and-mortar-like st...
International audienceThe mechanism of surfactant-induced cell lysis has been studied with quantitat...
The mechanism of surfactant-induced cell lysis has been studied with quantitative coherent anti-Stok...
In the context of increased interest in permeability enhancement technologies to achieve mucosal del...
Surfactin, a bacterial amphiphilic lipopeptide is attracting more and more attention in view of its ...
Surfactin, a bacterial amphiphilic lipopeptide is attracting more and more attention in view of its ...
AbstractSurfactin, a bacterial amphiphilic lipopeptide is attracting more and more attention in view...
Amphipathic, non-ionic surfactants are widely used in pharmaceutical and food industries to enhance ...
The lipopeptide surfactin exhibits promising antimicrobial activities which are hampered by haemolyt...
This work aims at a better understanding of the parameters and properties of surfactants that govern...
AbstractWe propose classifying surfactants with respect to their effect on membrane order, which is ...
Surfactin is an antibiotic produced by several strains of B. subtilis. Its broad range of biological...
The use of surfactants as drug permeability enhancers across epithelial barriers remains a challenge...
The stratum corneum (SC) is the ourtermost layer of the epidermis and has a brick-and-mortar-like st...
International audienceThe mechanism of surfactant-induced cell lysis has been studied with quantitat...
The mechanism of surfactant-induced cell lysis has been studied with quantitative coherent anti-Stok...