Over almost two centuries, synthetic chemists have been interested in reproducing molecules found in Nature. Natural products are an almost infinite source of synthetic challenges by their complex structural diversity. Chemists have employed diverse approaches to access a vast number of them. From target-oriented synthesis to diverted total synthesis, strategies in natural product synthesis have evolved to produce diverse compounds from common intermediates in a short number of steps. Furthermore, DFT calculations have sometimes been used to assist chemists to solve problems encountered during total syntheses. The purpose of this thesis was the total synthesis of natural products of the cytochalasin family and the development of related syn...
This dissertation comprises two chapters. The first chapter is a short review that covers the differ...
This thesis is concerned with the total syntheses of natural products and the development of a novel...
Le phénomène d'oxygénation tardive des produits naturels a été investigué sur deux modèles d'études ...
Over almost two centuries, synthetic chemists have been interested in reproducing molecules found in...
The Diels–Alder (DA) reaction is an important and frequently used synthetic transformation in the fo...
The late-stage oxygenation of natural products has been investigated on two studies templates: the p...
An increasing number of biologically and pharmacologically active peroxide natural products have bee...
Biomimetic synthesis, inspired by direct and fast biosynthetic processes, is an efficient way to pro...
International audienceAspochalasins are leucine-derived cytochalasins. Their complexity is often ass...
This thesis is divided into three chapters. The first chapter provides a brief review on recent wor...
The intermolecular addition of 1,3-dicarbonyl equivalents to endoperoxides in the presence of an org...
The treatment of 1,3-dienes with singlet oxygen to give endoperoxides represents a potent, chemo- an...
The investigation of the reactivity in synthesis of all-carbon 1,3-dipoles such as allyl cations der...
This dissertation comprises two chapters. The first chapter is a short review that covers the differ...
This thesis is concerned with the total syntheses of natural products and the development of a novel...
Le phénomène d'oxygénation tardive des produits naturels a été investigué sur deux modèles d'études ...
Over almost two centuries, synthetic chemists have been interested in reproducing molecules found in...
The Diels–Alder (DA) reaction is an important and frequently used synthetic transformation in the fo...
The late-stage oxygenation of natural products has been investigated on two studies templates: the p...
An increasing number of biologically and pharmacologically active peroxide natural products have bee...
Biomimetic synthesis, inspired by direct and fast biosynthetic processes, is an efficient way to pro...
International audienceAspochalasins are leucine-derived cytochalasins. Their complexity is often ass...
This thesis is divided into three chapters. The first chapter provides a brief review on recent wor...
The intermolecular addition of 1,3-dicarbonyl equivalents to endoperoxides in the presence of an org...
The treatment of 1,3-dienes with singlet oxygen to give endoperoxides represents a potent, chemo- an...
The investigation of the reactivity in synthesis of all-carbon 1,3-dipoles such as allyl cations der...
This dissertation comprises two chapters. The first chapter is a short review that covers the differ...
This thesis is concerned with the total syntheses of natural products and the development of a novel...
Le phénomène d'oxygénation tardive des produits naturels a été investigué sur deux modèles d'études ...