Maternal infection during pregnancy increases the offspring\u27s risk of developing neurodevelopmental disorders. While IL-6 is involved, the mechanism by which IL-6 and other cytokines affect developing neural circuits is unknown. In this issue of Immunity, Mirabella et al. (2021) show that the pro-inflammatory cytokine IL-6 specifically increases synaptogenesis in immature excitatory neurons through downstream neuronal STAT3-dependent transcriptional regulation of Rgs4
Epidemiological studies show that maternal immune activation (MIA) during pregnancy is a risk factor...
Several lines of evidence support the link between maternal inflammation during pregnancy and increa...
Cytokines are pleotrophic proteins that coordinate the host response to infection as well as mediate...
Poster Session 870. Developmental Disorders: Animal Models and Mechanisms: no. 870.18/BB10Autism is ...
Raw data Mirabella et al. IMMUNITYTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO...
Interleukin-6 (IL-6) is a cytokine originally identified almost 30 years ago as a B-cell differentia...
Summary: Circulating systemic factors can regulate adult neural stem cell (NSC) biology, but the ide...
Mirabella et al. Immunity 2021 High Resolution imagesTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ...
Besides its wide range of action as a proinflammatory cytokine in the immune system, interleukin-6 (...
Epidemiological studies show that maternal immune activation (MIA) during pregnancy is a risk factor...
Adverse neurodevelopmental outcomes are linked to perinatal production of inflammatory mediators, in...
Neurodevelopmental disorders such as autism and schizophrenia may result in part from maternal immun...
Schizophrenia and autism are thought to result from the interaction between a susceptibility genotyp...
Maternal infection during pregnancy is associated with increased risk of psychiatric and neurodevelo...
Background: Epidemiologic studies indicate maternal infection as a risk factor for autism and schizo...
Epidemiological studies show that maternal immune activation (MIA) during pregnancy is a risk factor...
Several lines of evidence support the link between maternal inflammation during pregnancy and increa...
Cytokines are pleotrophic proteins that coordinate the host response to infection as well as mediate...
Poster Session 870. Developmental Disorders: Animal Models and Mechanisms: no. 870.18/BB10Autism is ...
Raw data Mirabella et al. IMMUNITYTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO...
Interleukin-6 (IL-6) is a cytokine originally identified almost 30 years ago as a B-cell differentia...
Summary: Circulating systemic factors can regulate adult neural stem cell (NSC) biology, but the ide...
Mirabella et al. Immunity 2021 High Resolution imagesTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ...
Besides its wide range of action as a proinflammatory cytokine in the immune system, interleukin-6 (...
Epidemiological studies show that maternal immune activation (MIA) during pregnancy is a risk factor...
Adverse neurodevelopmental outcomes are linked to perinatal production of inflammatory mediators, in...
Neurodevelopmental disorders such as autism and schizophrenia may result in part from maternal immun...
Schizophrenia and autism are thought to result from the interaction between a susceptibility genotyp...
Maternal infection during pregnancy is associated with increased risk of psychiatric and neurodevelo...
Background: Epidemiologic studies indicate maternal infection as a risk factor for autism and schizo...
Epidemiological studies show that maternal immune activation (MIA) during pregnancy is a risk factor...
Several lines of evidence support the link between maternal inflammation during pregnancy and increa...
Cytokines are pleotrophic proteins that coordinate the host response to infection as well as mediate...
DOI
Add to ORKG