Immunophilins (IMMs) are a family of intracellular proteins that bind immunosuppressive drugs. They are referred to as FK506-binding proteins (FKBPs) when they bind FK506, and cyclophilins (CyPs) when they bind cyclosporine A (CsA). In previous studies performed in cell cultures, we demonstrated that FK506 shows neuroregenerative and neuroprotective actions via FKBPs, the expression balance between FKBP52 and FKBP51 playing a key role during those processes.Fil: Daneri Becerra, Cristina del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Zgajnar, Nadia Ro...
Alpha-synuclein (α-synuclein) is considered a key player in Parkinson's disease (PD), but the exact ...
Immunophilins are a family of proteins whose signature domain is the peptidylprolylisomerase domain....
A novel macrolide antibiotic, FK-506, isolated from Streptomyces tsukubaensis, has been shown to be ...
Immunophilins (IMMs) are a family of intracellular proteins that bind immunosuppressive drugs. They ...
The immunosuppressant drug FK506 (or tacrolimus) is a macrolide that binds selectively to immunophil...
Immunophilins (IP) are receptors for immunosuppressive drugs like cyclosporin A, FK506, rapamycin an...
Immunophilins consist of a family of highly conserved proteins binding with immunosuppressive...
Background: Ligands for FK506-binding proteins, also referred to as neuroimmunophilin ligands, have ...
Immunophilins are a family of receptors for immunosuppressive drugs like cyclosporin A, FK506, rapa...
Immunophilins comprise a family of intracellular proteins with peptidyl-prolyl-(cis/trans)-isomerase...
Immunophilins are a family of proteins whose signature domain is the peptidylprolyl-isomerase domain...
The fine regulation of signalling cascades is a key event required to maintain the appropriate funct...
The class of proteins known as immunophilins, that are cis-trans prolyl isomerases perform diverse c...
FK506 binding (FKBP) proteins are part of the highly conserved immunophilin family and its members h...
BackgroundHIV-associated neurocognitive disorders (HAND) continue to be a common morbidity associate...
Alpha-synuclein (α-synuclein) is considered a key player in Parkinson's disease (PD), but the exact ...
Immunophilins are a family of proteins whose signature domain is the peptidylprolylisomerase domain....
A novel macrolide antibiotic, FK-506, isolated from Streptomyces tsukubaensis, has been shown to be ...
Immunophilins (IMMs) are a family of intracellular proteins that bind immunosuppressive drugs. They ...
The immunosuppressant drug FK506 (or tacrolimus) is a macrolide that binds selectively to immunophil...
Immunophilins (IP) are receptors for immunosuppressive drugs like cyclosporin A, FK506, rapamycin an...
Immunophilins consist of a family of highly conserved proteins binding with immunosuppressive...
Background: Ligands for FK506-binding proteins, also referred to as neuroimmunophilin ligands, have ...
Immunophilins are a family of receptors for immunosuppressive drugs like cyclosporin A, FK506, rapa...
Immunophilins comprise a family of intracellular proteins with peptidyl-prolyl-(cis/trans)-isomerase...
Immunophilins are a family of proteins whose signature domain is the peptidylprolyl-isomerase domain...
The fine regulation of signalling cascades is a key event required to maintain the appropriate funct...
The class of proteins known as immunophilins, that are cis-trans prolyl isomerases perform diverse c...
FK506 binding (FKBP) proteins are part of the highly conserved immunophilin family and its members h...
BackgroundHIV-associated neurocognitive disorders (HAND) continue to be a common morbidity associate...
Alpha-synuclein (α-synuclein) is considered a key player in Parkinson's disease (PD), but the exact ...
Immunophilins are a family of proteins whose signature domain is the peptidylprolylisomerase domain....
A novel macrolide antibiotic, FK-506, isolated from Streptomyces tsukubaensis, has been shown to be ...