Molecular epidemiology of hepatitis B virus in Misiones, Argentina
- Mojsiejczuk, Laura Noelia
- Torres, Carolina
- Sevic, Ina
- Badano, Ines
- Malan, Richard
- Flichman, Diego Martin
- Liotta, Domingo Javier
- Campos, Rodolfo Hector
DOIAbstract
Hepatitis B virus (HBV) infection is a major public health problem worldwide. The aims of this study were to describe the molecular epidemiology of HBV in the Province of Misiones, Argentina and estimate the phylodynamic of the main groups in a Bayesian coalescent framework. To this end, partial or complete genome sequences were obtained from 52 blood donor candidates.The phylogenetic analysis based on partial sequences of S/P region showed a predominance of genotype D (65.4%), followed by genotype F (30.8%) and genotype A as a minority (3.8%). At subgenotype level, the circulation of subgenotypes D3 (42.3%), D2 (13.5%), F1b (11.5%) and F4 (9.6%) was mainly identified.The Bayesian coalescent analysis of 29 complete genome sequences for the ...
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