Add to ORKGObesity is a multi-systemic disorder of energy balance. Despite intense investigation, the determinants of energy homeostasis remain incompletely understood, and efficacious treatments against obesity and its complications are lacking. Here, we demonstrate that conferred arginine iminohydrolysis by the bacterial virulence factor and arginine deiminase
We examined whether arginase inhibition influences hepatic metabolic pathways and whole body adiposi...
Purpose: l-alanine (Ala) and l-arginine (Arg) have been reported to regulate pancreatic β-cell physi...
This study was conducted to test the hypothesis that dietary arginine supplementation reduces fat ma...
Obesity is a prevalent metabolic disorder worldwide. Here, we describe a comprehensive protocol usin...
Glucagon analogues show promise as components of next-generation, multi-target, anti-obesity therape...
Adiponectin is a hormone that lowers glucose production by increasing liver insulin sensitivity. Ins...
Objectives: We examined whether arginase inhibition influences hepatic metabolic pathways and whole ...
Autophagy is critical for the maintenance of organelle function and intracellular nutrient environme...
Unbalanced energy intake over expenditure causes obesity, and the prevalence and incidences of obesi...
Autophagy insufficiency due to aging, high-fat injury or genetic predisposition could be a factor in...
Due to the absolute need for arginine that certain cancer cells have, arginine depletion is a therap...
Autophagy is a critical regulator of cellular homeostasis, dysregulation of which is associated with...
Obesity is an established risk factor for pancreatic ductal adenocarcinoma (PDA). Despite recent ide...
SummaryAutophagy is a homeostatic process involved in the bulk degradation of cytoplasmic components...
Arginine auxotrophy occurs in certain tumor types and is usually caused by the silencing of arginino...
We examined whether arginase inhibition influences hepatic metabolic pathways and whole body adiposi...
Purpose: l-alanine (Ala) and l-arginine (Arg) have been reported to regulate pancreatic β-cell physi...
This study was conducted to test the hypothesis that dietary arginine supplementation reduces fat ma...
Obesity is a prevalent metabolic disorder worldwide. Here, we describe a comprehensive protocol usin...
Glucagon analogues show promise as components of next-generation, multi-target, anti-obesity therape...
Adiponectin is a hormone that lowers glucose production by increasing liver insulin sensitivity. Ins...
Objectives: We examined whether arginase inhibition influences hepatic metabolic pathways and whole ...
Autophagy is critical for the maintenance of organelle function and intracellular nutrient environme...
Unbalanced energy intake over expenditure causes obesity, and the prevalence and incidences of obesi...
Autophagy insufficiency due to aging, high-fat injury or genetic predisposition could be a factor in...
Due to the absolute need for arginine that certain cancer cells have, arginine depletion is a therap...
Autophagy is a critical regulator of cellular homeostasis, dysregulation of which is associated with...
Obesity is an established risk factor for pancreatic ductal adenocarcinoma (PDA). Despite recent ide...
SummaryAutophagy is a homeostatic process involved in the bulk degradation of cytoplasmic components...
Arginine auxotrophy occurs in certain tumor types and is usually caused by the silencing of arginino...
We examined whether arginase inhibition influences hepatic metabolic pathways and whole body adiposi...
Purpose: l-alanine (Ala) and l-arginine (Arg) have been reported to regulate pancreatic β-cell physi...
This study was conducted to test the hypothesis that dietary arginine supplementation reduces fat ma...