The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular myocyte. The principal modifications based on the recently published data comprise: formulation of the function of peripheral dyads, incorporation of peripheral and tubular intracellular subspaces, reformulation of inactivation properties of surface of tubular ICa and description of the function of exogenous Ca2+ buffer in the intracellular space
This thesis develops biophysically-based data-driven mathematical models of intracellular calciumdyn...
Background: The past thirty-five years have seen an intense search for the molecular mechanisms unde...
Understanding physiological mechanisms underlying the activity of the heart is of great medical impo...
The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular ...
The t-tubules of mammalian ventricular myocytes are invaginations of the cell membrane that occur at...
AbstractWe have developed a detailed mathematical model for Ca2+ handling and ionic currents in the ...
We present a design of a model of rat ventricular cardiomyocyte with transverse-axial tubular system...
Intracellular Ca2+ load and Ca2+ transient are considerably dependent on distribution of sarcolemmal...
In this work, we present a new version of cardiac ventricular cell model incorporating the transvers...
Abstract: We have developed a computer model of human cardiac ventricular myocyte (CVM), including t...
Copyright © 2014 Michal Pásek et al. This is an open access article distributed under the Creative ...
International audienceA model of the guinea-pig cardiac ventricular myocyte has been developed that ...
We have used a previously published computer model of the rat cardiac ventricular myocyte to investi...
Background: The objective of this study is to develop a comprehensive model of the electromechanica...
Atrial fibrillations and heart failure are among the leading cardiovascular diseases in the world. U...
This thesis develops biophysically-based data-driven mathematical models of intracellular calciumdyn...
Background: The past thirty-five years have seen an intense search for the molecular mechanisms unde...
Understanding physiological mechanisms underlying the activity of the heart is of great medical impo...
The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular ...
The t-tubules of mammalian ventricular myocytes are invaginations of the cell membrane that occur at...
AbstractWe have developed a detailed mathematical model for Ca2+ handling and ionic currents in the ...
We present a design of a model of rat ventricular cardiomyocyte with transverse-axial tubular system...
Intracellular Ca2+ load and Ca2+ transient are considerably dependent on distribution of sarcolemmal...
In this work, we present a new version of cardiac ventricular cell model incorporating the transvers...
Abstract: We have developed a computer model of human cardiac ventricular myocyte (CVM), including t...
Copyright © 2014 Michal Pásek et al. This is an open access article distributed under the Creative ...
International audienceA model of the guinea-pig cardiac ventricular myocyte has been developed that ...
We have used a previously published computer model of the rat cardiac ventricular myocyte to investi...
Background: The objective of this study is to develop a comprehensive model of the electromechanica...
Atrial fibrillations and heart failure are among the leading cardiovascular diseases in the world. U...
This thesis develops biophysically-based data-driven mathematical models of intracellular calciumdyn...
Background: The past thirty-five years have seen an intense search for the molecular mechanisms unde...
Understanding physiological mechanisms underlying the activity of the heart is of great medical impo...