Cogan-Guerry Microcystic Corneal Epithelial Dystrophy: A Clinical and Electron Microscopic Study

In summary, microcystic epithelial dystrophy of the cornea as described by Cogan and Guerry has become a well documented clinical entity. In this paper, a case report and preliminary electron microscopic findings of a patient with this dystrophy were presented. This case showed a thickened, two-layered basement membrane which was completely missing in some areas. The second characteristic change was that of cystic epithelial areas containing debris. The possible significance of these findings and a diagnostic technique for detecting of these corneal changes were discussed