Human T Lymphotropic virus and pulmonary diseases

Federal University of Pará. Tropical Medicine Center. Belém, PA, Brazil / State University of Pará. Center of Health and Biological Sciences. Belém, PA, Brazil.State University of Pará. Center of Health and Biological Sciences. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Programa de Pós-Graduação em Virologia. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Programa de Pós-Graduação em Virologia. Ananindeua, PA, Brasil.Federal University of Pará. Tropical Medicine Center. Belém, PA, Brazil / State University of Pará. Center of Health and Biological Sciences. Belém, PA, Brazil.Federal University of Pará. Tropical Medicine Center. Belém, PA, Brazil / State University of Pará. Center of Health and Biological Sciences. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Programa de Pós-Graduação em Virologia. Ananindeua, PA, Brasil.Human T lymphotropic virus type 1 (HTLV-1) is the etiological agent of HTLV1-associated myelopathy, and adult T cell lymphoma/leukemia (ATL/L). Pulmonary complications such as alveolitis and bronchiectasis were found in individuals who develop TSP/HAM due to chronic inflammation. These individuals showed image anomalies in CT scans and changes in pulmonary function parameters distinctive of pulmonary disease. Furthermore, infected individuals have a greater susceptibility to pulmonary tuberculosis either due to changes in the innate immune response, in asymptomatic carriers, or to an opportunistic disease linked to immunodepression, in individuals who develop ATL/L. This summary addresses the general lack of knowledge regarding the relationship between HTLV-1 and pulmonary diseases and provides direction for future work