Postmortem findings for 7 neonates with congenital Zika Virus Infection

Federal University of Ceará. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil / Serviço de Verificação de Óbitos. Fortaleza, CE, Brazil.Ceará State Central Public Health Laboratory. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil / Serviço de Verificação de Óbitos. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil / Serviço de Verificação de Óbitos. Fortaleza, CE, Brazil.University of Fortaleza. Fortaleza, CE, Brazil / Ceará State Secretariat of Health. Fortaleza, CE, Brazil.Ceará State Central Public Health Laboratory. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.University of Virginia School of Medicine. Charlottesville, VA, USA.Chan School of Public Health. Harvard T.H. Boston, MA, USA / University of California, San Francisco. CA, USA.Federal University of Ceará. Fortaleza, CE, Brazil.Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection