The symptoms of infectious diseases are frequently caused by an overzealous host immune response against the invading microorganism, rather than by the microorganism itself. This is the case for one of the most common mucosal infection, vulvovaginal candidiasis (VVC), where the yeast Candida albicans triggers a non‐protective influx of host immune cells, resulting in aggressive local inflammation and symptomatic disease. The aim of our study was to investigate the role of the zincophore Pra1 in VVC immunopathology. Pra1 is a secreted C. albicans zinc binding protein released during zinc limitation and used by the fungus to forage for this essential micronutrient from the environment. In vitro tissue culture systems, a murine model of exp...
Abstract The expression of host inflammatory and Candida albicans putative virulence factors was stu...
<div><p>The ability of pathogenic microorganisms to assimilate essential nutrients from their hosts ...
Background Vulvovaginal candidiasis is a common superficial candidiasis; however, a host’s immunolog...
The symptoms of infectious diseases are frequently caused by an overzealous host immune response ag...
Vulvovaginal candidiasis (VVC) affects around 75% of all women at least once in their life and 8% de...
Introduction. The microbiological, pathological and clinical factors determining vaginal candidiasis...
Opportunistic infections with the saprophytic yeast Candida albicans are a major cause of morbidity ...
Vaginal candidiasis is a common disorder in women of childbearing age, caused primarily by the dimor...
Opportunistic infections with the saprophytic yeast Candida albicans are a major cause of morbidity ...
Vulvovaginal candidiasis (VVC) is a symptomatic inflammation of the vagina mainly caused by C. albic...
Vaginal candidiasis is a common disorder in women of childbearing age, caused primarily by the dimor...
The ability of pathogenic microorganisms to assimilate essential nutrients from their hosts is criti...
As both a commensal and a pathogen of humans, C. albicans colonises diverse anatomical sites, each o...
ABSTRACT Despite acute inflammation by polymorphonuclear neutrophils (PMNs) during vulvovaginal cand...
Introduction. Candidiasis remains a notable health problem in subjects with underlying disease and s...
Abstract The expression of host inflammatory and Candida albicans putative virulence factors was stu...
<div><p>The ability of pathogenic microorganisms to assimilate essential nutrients from their hosts ...
Background Vulvovaginal candidiasis is a common superficial candidiasis; however, a host’s immunolog...
The symptoms of infectious diseases are frequently caused by an overzealous host immune response ag...
Vulvovaginal candidiasis (VVC) affects around 75% of all women at least once in their life and 8% de...
Introduction. The microbiological, pathological and clinical factors determining vaginal candidiasis...
Opportunistic infections with the saprophytic yeast Candida albicans are a major cause of morbidity ...
Vaginal candidiasis is a common disorder in women of childbearing age, caused primarily by the dimor...
Opportunistic infections with the saprophytic yeast Candida albicans are a major cause of morbidity ...
Vulvovaginal candidiasis (VVC) is a symptomatic inflammation of the vagina mainly caused by C. albic...
Vaginal candidiasis is a common disorder in women of childbearing age, caused primarily by the dimor...
The ability of pathogenic microorganisms to assimilate essential nutrients from their hosts is criti...
As both a commensal and a pathogen of humans, C. albicans colonises diverse anatomical sites, each o...
ABSTRACT Despite acute inflammation by polymorphonuclear neutrophils (PMNs) during vulvovaginal cand...
Introduction. Candidiasis remains a notable health problem in subjects with underlying disease and s...
Abstract The expression of host inflammatory and Candida albicans putative virulence factors was stu...
<div><p>The ability of pathogenic microorganisms to assimilate essential nutrients from their hosts ...
Background Vulvovaginal candidiasis is a common superficial candidiasis; however, a host’s immunolog...