Predictors of hospital-acquired bacterial and fungal superinfections in COVID-19: A prospective observational study
- Falcone M.
- Tiseo G.
- Giordano C.
- Leonildi A.
- Menichini M.
- Vecchione A.
- Pistello M.
- Guarracino F.
- Ghiadoni L.
- Forfori F.
- Barnini S.
- Menichetti F.
- Degl'Innocenti S. A. O.
- Barbieri G.
- Biancalana M.
- Borselli M.
- Nencini E.
- Spinelli S.
- Antognoli R.
- Calsolario V.
- Monzani F.
- Paterni S.
- Baldassarri R.
- Bertini P.
- Brizzi G.
- Rocca A. D.
- Malacarne P.
- Monfroni M.
- Piagnani C.
- Carpene N.
- Carrozzi L.
- Celi A.
- Desideri M.
- Gherardi M.
- Serradori M.
- Cinotti F.
- Cipriano A.
- Park N.
- Forotti G.
- Mengozzi A.
- Masi S.
- Ruberti F.
- Sciuto M.
- Virdis A.
- Maggi F.
- Galfo V.
DOIAbstract
Background: Bacterial and fungal superinfections may complicate the course of hospitalized patients with COVID-19. Objectives: To identify predictors of superinfections in COVID-19. Methods: Prospective, observational study including patients with COVID-19 consecutively admitted to the University Hospital of Pisa, Italy, between 4 March and 30 April 2020. Clinical data and outcomes were registered. Superinfection was defined as a bacterial or fungal infection that occurred ≥48 h after hospital admission. A multivariate analysis was performed to identify factors independently associated with superinfections. Results: Overall, 315 patients with COVID-19 were hospitalized and 109 episodes of superinfections were documented in 69 (21.9%) patien...
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