Effects of postural changes on measured intraocular pressure and repeatability of PT-100 tonometer and agreement with applanation and indentation tonometry

Background: Repeatability and validity are important components of precision in any measurement system. Aim: This study aimed to determine the effect of change in head and neck position and body posture on the repeatability of intraocular pressure (IOP) measurements with PT-100 noncontact tonometer and compare with Goldmann, PT-100 and Schi⊘tz tonometer readings. Setting: Optometry clinic, Saudi Arabia. Methods: The IOP was measured in one selected eye of 84 healthy participants (mean aged 21.9 ± 2.0 years) using PT-100 in three head and body positions, Goldmann tonometer and Schi⊘tz on two separate visits, in a randomised fashion. Central corneal thickness (CCT) was measured using an ultrasound pachymeter. The repeatability, agreement and correlations between CCT and IOP differentials were assessed. Results: The IOP measured in three head and body positions with the PT-100 were similar and comparable to Goldmann IOPs in sessions one and two with 74% and 86% of PT-100 measurements within ±3 mmHg of the Goldmann tonometry, respectively, for sessions one and two. The Schi⊘tz tonometer-measured IOP was higher than the Goldmann IOPs (p < 0.05) with 60% and 44% of Schi⊘tz IOPs within ±3 mmHg of the Goldmann tonometer IOP in sessions one and two, respectively. The limits of repeatability and reproducibility were best with the PT-100 and worst with the Schi⊘tz tonometer. The mean CCT (552±36 µm) was negatively correlated with differences between Goldmann and both PT-100 and Schi0tz-measured IOP. Conclusion: Postural changes did not affect the validity and repeatability of PT-100 readings. PT-100 measurements were interchangeable with Goldmann tonometer. Schi⊘tz overestimated Goldmann IOP in thicker corneas more than the PT-100