Urban areas around the globe are growing rapidly and as a consequence the anthropogenic effects on the environment are ever-increasing. Understanding the dynamics, procedures and mechanics behind urban greenhouse gas emissions is a challenge for the scientific community. This study investigates the variability of urban CO2 emissions in the city centre of Heraklion, a typical Mediterranean city in Greece, during a four-year period with gradual changes in the traffic regulations and changes in traffic patterns due to the recent restriction measures imposed to limit the spread of the COVID-19 pandemic. The CO2 flux (Fc) was measured using the Eddy Covariance (EC) method with a single tower-based system, permanently installed in the centre of t...