Add to ORKGBackground: β-thalassemia is characterized by reduced synthesis of the hemoglobin beta chain that results in microcytic hypochromic anemia and reduced amounts of hemoglobin A (HbA) on hemoglobin analysis. β-tha-lassemias are caused by mutations in the β-globin gene, inherited in an autosomal recessive manner. Determining molecular defects in couples carrying β-thalassemia is a prerequisite for prenatal diagnosis of the disease. In this regards, database of β-globin gene haplotypes facilitates mutation detection of the gene and helps genetic coun-selors to reach the goals of β-thalassemia prevention program. Methods: In this cross-sectional study, 255 couples attended genetic counseling between December 2017 and January 2019 in Afzalip...
Introduction: β –Thalassaemia was first explained by Thomas Cooly as Cooly’s anaemia in 1925. The β-...
Background: Hemoglobin-associated disorder is a different group of recessive genetic diseases. which...
Abstract Background Beta-thalassemia is common in the Mediterranean area as well as the Middle East ...
Background: Mutations in β-globin gene may result in β-thalassemia major, which is one of the most c...
Hemoglobinopathies are inherited blood disorders with an autosomal recessive pattern. We aimed to ev...
Background and objective: ß-thalassemia results from a diverse range of mutations inside the hemoglo...
Introduction: Recent molecular studies on Iranian β-thalassemia genes revealed the presence of eight...
ABSTRACT Background and Objectives: Hemoglobinopathies are characterized by defects in ...
Introduction: Alpha-thalassemia (α-thalassemia) is caused by a range of mutations in the α-globin ge...
Background: Beta thalassemia is a common inherited disease,resulting from one or more of 200 differe...
Introduction: Thalassemias are defined by the absence or decrease of globin chain(s), which may lead...
α-Thalassemia is a widespread inherited disease particularly prevalent in the middle East Asia popul...
Background: Hemoglobinopathy and thalassemia are prevalent genetic disorders throughout the world. B...
Background and Objectives: Beta thalassemia is the most common autosomal recessive disorder. Up to n...
Background: Thalassemia is a genetic disorder of autosomal recessive and has high prevalence in Iran...
Introduction: β –Thalassaemia was first explained by Thomas Cooly as Cooly’s anaemia in 1925. The β-...
Background: Hemoglobin-associated disorder is a different group of recessive genetic diseases. which...
Abstract Background Beta-thalassemia is common in the Mediterranean area as well as the Middle East ...
Background: Mutations in β-globin gene may result in β-thalassemia major, which is one of the most c...
Hemoglobinopathies are inherited blood disorders with an autosomal recessive pattern. We aimed to ev...
Background and objective: ß-thalassemia results from a diverse range of mutations inside the hemoglo...
Introduction: Recent molecular studies on Iranian β-thalassemia genes revealed the presence of eight...
ABSTRACT Background and Objectives: Hemoglobinopathies are characterized by defects in ...
Introduction: Alpha-thalassemia (α-thalassemia) is caused by a range of mutations in the α-globin ge...
Background: Beta thalassemia is a common inherited disease,resulting from one or more of 200 differe...
Introduction: Thalassemias are defined by the absence or decrease of globin chain(s), which may lead...
α-Thalassemia is a widespread inherited disease particularly prevalent in the middle East Asia popul...
Background: Hemoglobinopathy and thalassemia are prevalent genetic disorders throughout the world. B...
Background and Objectives: Beta thalassemia is the most common autosomal recessive disorder. Up to n...
Background: Thalassemia is a genetic disorder of autosomal recessive and has high prevalence in Iran...
Introduction: β –Thalassaemia was first explained by Thomas Cooly as Cooly’s anaemia in 1925. The β-...
Background: Hemoglobin-associated disorder is a different group of recessive genetic diseases. which...
Abstract Background Beta-thalassemia is common in the Mediterranean area as well as the Middle East ...