SOCS-Regulation of Jak/STAT Signalling in Idiopathic Pulmonary Fibrosis (IPF)

The Global Idiopathic Pulmonary Fibrosis (IPF) Collaborative Network: A Platform for IPF Genetics

Walker, T.D.
de Andrade, J.A.
Bendstrup, E.
Blackwell, T.S.
Borie, R.
Brown, K.K.
Christie, J.D.
Collard, H.R.
Corte, T.J.
Crestani, B.
Du Bois, R.M.
Eickelberg, O.
Gibson, K.F.
Henry, M.
Gudmundsson, G.
Hirani, N.
Inoue, Y.
Jenkins, R.G.
Kass, D.
Kawut, S.M.
Keane, J.M.
Kim, D.S.
Laurent, G.
Lederer, D.J.
Loyd, J.E.
Mogulkoc, N.
Molina-Molina, M.
Nathan, S.
Noth, I.
Ohta, K.
Parfrey, H.
Prêle, C.M.
Selman, M.
Song, J.W.
Sterclova, M.
Tobin, M.D.
Vašáková, M.
Wolters, P.J.
Powers, J.
Waltz, A.
Schwarz, M.I.
Schwartz, D.A.

January 2017

American Thoracic Society International Conference Abstracts > C101. IPF: CLINICAL STUDIES, THERAPEU...

Localization of activated, phosphorylated STAT3 in fibroblast foci and overlying bronchiolar epithelium in idiopathic pulmonary fibrosis (IPF) lungs.

Martina Korfei (2202892)
Daniel Stelmaszek (6014096)
BreAnne MacKenzie (158285)
Sylwia Skwarna (6014099)
Shashipavan Chillappagari (6014102)
Anna C. Bach (6014105)
Clemens Ruppert (33937)
Shigeki Saito (560645)
Poornima Mahavadi (2202901)
Walter Klepetko (110147)
Ludger Fink (5496)
Werner Seeger (5494)
Joseph A. Lasky (363234)
Soni S. Pullamsetti (6014108)
Oliver H. Krämer (166933)
Andreas Guenther (33941)

November 2018

Representative immunohistochemistry for α-SMA, phosphorylated (p)-STAT3 (Y705) and cytokeratin-5 (KR...

STAT3-Mediated signaling dysregulates lung Fibroblast-Myofibroblast activation and differentiation in UIP/IPF

Pechkovsky, D.V.
Prêle, C.M.
Wong, J.
Hogaboam, C.M.
McAnulty, R.J.
Laurent, G.J.
Zhang, S.S-M
Selman, M.
Mutsaers, S.E.
Knight, D.A.

January 2012

STAT3 is a latent transcription factor that plays a role in regulating fibroblast function in fibrot...

LSC Abstract – Investigating SOCS-mediated regulation of STAT signalling in idiopathic pulmonary fibrosis (IPF)

Prêle, C.
Iosifidis, T.
McAnulty, R.
Badrian, B.
Jamieson, S.
Pearce, D.
Ernst, M.
Thompson, P.
Laurent, G.
Knight, D.
Mutsaers, S.

January 2016

The STAT inhibitor, SOCS1 is reduced in IPF lung fibroblasts, and has been linked to higher levels o...

Role of JAK/STAT in Interstitial Lung Diseases; Molecular and Cellular Mechanisms

Paula Montero
Javier Milara
Inés Roger
Julio Cortijo

June 2021

Interstitial lung diseases (ILDs) comprise different fibrotic lung disorders characterized by cellul...

The Jak2 Pathway Is Activated In Idiopathic Pulmonary Fibrosis

Milara, Javier
Hernandez, Gracia
Ballester, Beatriz
Morell, Aanselm
Roger, Inés
Montero, P
Escrivá, Juan
Lloris, José M.
Molina Molina, María
Morcillo, Esteban
Cortijo, Julio

Background: Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal fibrotic d...

Reduced SOCS1 Expression in Lung Fibroblasts from Patients with IPF Is Not Mediated by Promoter Methylation or Mir155

Prêle, Cecilia M.
Iosifidis, Thomas
McAnulty, Robin J.
Pearce, David R.
Badrian, Bahareh
Miles, Tylah
Jamieson, Sarra E.
Ernst, Matthias
Thompson, Philip J.
Laurent, Geoffrey J.
Knight, Darryl A.
Mutsaers, Steven E.

April 2021

The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transc...

The JAK2 pathway is activated in idiopathic pulmonary fibrosis

Javier Milara
Gracia Hernandez
Beatriz Ballester
Anselm Morell
Inés Roger
P. Montero
Juan Escrivá
José M. Lloris
Maria Molina-Molina
Esteban Morcillo
Julio Cortijo

February 2018

Abstract Background Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal fi...

STAT3: A central mediator of pulmonary fibrosis?

Prêle, C.M.
Yao, E.
O’Donoghue, R.J.J.
Mutsaers, S.E.
Knight, D.A.

January 2012

Pulmonary fibrosis is a devastating, relentlessly progressive, and lethal disease. There is a signif...

Dysregulated STAT3 Signaling Induces and Reinforces Fibroblast Senescence in Lung Fibroblasts of IPF Patients

Waters, D.W.
Schuliga, M.
Fogarty, E.
Burgess, J.K.
Grainge, C.
Westall, G.
Laurent, G.
Prêle, C.M.
Mutsaers, S.E.
Knight, D.

January 2017

American Thoracic Society International Conference Abstracts > A74. REGULATORY MECHANISMS OF THE MOL...

Reduced SOCS1 expression in lung fibroblasts from patients with IPF is not mediated by promoter methylation or Mir155

Prêle, C.M.
Iosifidis, T.
McAnulty, R.J.
Pearce, D.R.
Badrian, B.
Miles, T.
Jamieson, S.E.
Ernst, M.
Thompson, P.J.
Laurent, G.J.
Knight, D.A.
Mutsaers, S.E.

January 2021

The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transc...

Pathophysiological Roles of Stress-Activated Protein Kinases in Pulmonary Fibrosis

Yoshitoshi Kasuya
Jun-Dal Kim
Masahiko Hatano
Koichiro Tatsumi
Shuichi Matsuda

June 2021

Idiopathic pulmonary fibrosis (IPF) is one of the most symptomatic progressive fibrotic lung disease...

An Update on the Global Idiopathic Pulmonary Fibrosis (IPF) Collaborative Network: A Platform for IPF Genetics

Walker, T.
Schwartz, D.A.
Schwarz, M.I.
Fingerlin, T.E.
Powers, J.
de Andrade, J.A.
Bendstrup, E.
Blackwell, T.S.
Borie, R.
Brown, K.K.
Christie, J.D.
Collard, H.R.
Corte, T.J.
Crestani, B.
Eickelberg, O.
Gibson, K.F.
Gudmundsson, G.
Henry, M.
Hirani, N.
Inoue, Y.
Jenkins, R.G.
Kass, D.
Kawut, S.M.
Keane, J.M.
Kennedy, M.P.
Laurent, G.J.
Lederer, D.J.
Loyd, J.E.
Mogulkoc, N.
Musani, A.I.
Molina, J.
Nathan, S.D.
Noth, I.
Ohta, K.
Parfrey, H.
Poletti, V.
Prêle, C.
Ryerson, C.J.
Selman, M.
Shea, B.
Song, J.W.
Steele, M.P.
Sterclova, M.
Tobin, M.D.
Tomassetti, S.
Tobin, M.D.
Vašáková, M.
Waltz, A.
Wolters, P.J.
Zhang, Y.

January 2018

American Thoracic Society International Conference Abstracts > C72. PULMONARY FIBROSIS: MECHANISMS A...

STAT3 in tissue fibrosis: Is there a role in the lung?

Knight, D.
Mutsaers, S.E.
Prêle, C.M.

January 2011

Fibrosis is defined as an excessive deposition of connective tissue components that results in the d...

Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis.

Agostini, Carlo
Gurrieri, C.

January 2006

Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible fibrosing lung disease of unkn...

The Global Idiopathic Pulmonary Fibrosis (IPF) Collaborative Network: A Platform for IPF Genetics

Walker, T.D.
de Andrade, J.A.
Bendstrup, E.
Blackwell, T.S.
Borie, R.
Brown, K.K.
Christie, J.D.
Collard, H.R.
Corte, T.J.
Crestani, B.
Du Bois, R.M.
Eickelberg, O.
Gibson, K.F.
Henry, M.
Gudmundsson, G.
Hirani, N.
Inoue, Y.
Jenkins, R.G.
Kass, D.
Kawut, S.M.
Keane, J.M.
Kim, D.S.
Laurent, G.
Lederer, D.J.
Loyd, J.E.
Mogulkoc, N.
Molina-Molina, M.
Nathan, S.
Noth, I.
Ohta, K.
Parfrey, H.
Prêle, C.M.
Selman, M.
Song, J.W.
Sterclova, M.
Tobin, M.D.
Vašáková, M.
Wolters, P.J.
Powers, J.
Waltz, A.
Schwarz, M.I.
Schwartz, D.A.

January 2017

American Thoracic Society International Conference Abstracts > C101. IPF: CLINICAL STUDIES, THERAPEU...

Localization of activated, phosphorylated STAT3 in fibroblast foci and overlying bronchiolar epithelium in idiopathic pulmonary fibrosis (IPF) lungs.

Martina Korfei (2202892)
Daniel Stelmaszek (6014096)
BreAnne MacKenzie (158285)
Sylwia Skwarna (6014099)
Shashipavan Chillappagari (6014102)
Anna C. Bach (6014105)
Clemens Ruppert (33937)
Shigeki Saito (560645)
Poornima Mahavadi (2202901)
Walter Klepetko (110147)
Ludger Fink (5496)
Werner Seeger (5494)
Joseph A. Lasky (363234)
Soni S. Pullamsetti (6014108)
Oliver H. Krämer (166933)
Andreas Guenther (33941)

November 2018

Representative immunohistochemistry for α-SMA, phosphorylated (p)-STAT3 (Y705) and cytokeratin-5 (KR...

STAT3-Mediated signaling dysregulates lung Fibroblast-Myofibroblast activation and differentiation in UIP/IPF

Pechkovsky, D.V.
Prêle, C.M.
Wong, J.
Hogaboam, C.M.
McAnulty, R.J.
Laurent, G.J.
Zhang, S.S-M
Selman, M.
Mutsaers, S.E.
Knight, D.A.

January 2012

STAT3 is a latent transcription factor that plays a role in regulating fibroblast function in fibrot...

LSC Abstract – Investigating SOCS-mediated regulation of STAT signalling in idiopathic pulmonary fibrosis (IPF)

Prêle, C.
Iosifidis, T.
McAnulty, R.
Badrian, B.
Jamieson, S.
Pearce, D.
Ernst, M.
Thompson, P.
Laurent, G.
Knight, D.
Mutsaers, S.

January 2016

The STAT inhibitor, SOCS1 is reduced in IPF lung fibroblasts, and has been linked to higher levels o...

Role of JAK/STAT in Interstitial Lung Diseases; Molecular and Cellular Mechanisms

Paula Montero
Javier Milara
Inés Roger
Julio Cortijo

June 2021

Interstitial lung diseases (ILDs) comprise different fibrotic lung disorders characterized by cellul...

The Jak2 Pathway Is Activated In Idiopathic Pulmonary Fibrosis

Milara, Javier
Hernandez, Gracia
Ballester, Beatriz
Morell, Aanselm
Roger, Inés
Montero, P
Escrivá, Juan
Lloris, José M.
Molina Molina, María
Morcillo, Esteban
Cortijo, Julio

Background: Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal fibrotic d...

Reduced SOCS1 Expression in Lung Fibroblasts from Patients with IPF Is Not Mediated by Promoter Methylation or Mir155

Prêle, Cecilia M.
Iosifidis, Thomas
McAnulty, Robin J.
Pearce, David R.
Badrian, Bahareh
Miles, Tylah
Jamieson, Sarra E.
Ernst, Matthias
Thompson, Philip J.
Laurent, Geoffrey J.
Knight, Darryl A.
Mutsaers, Steven E.

April 2021

The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transc...

The JAK2 pathway is activated in idiopathic pulmonary fibrosis

Javier Milara
Gracia Hernandez
Beatriz Ballester
Anselm Morell
Inés Roger
P. Montero
Juan Escrivá
José M. Lloris
Maria Molina-Molina
Esteban Morcillo
Julio Cortijo

February 2018

Abstract Background Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal fi...

STAT3: A central mediator of pulmonary fibrosis?

Prêle, C.M.
Yao, E.
O’Donoghue, R.J.J.
Mutsaers, S.E.
Knight, D.A.

January 2012

Pulmonary fibrosis is a devastating, relentlessly progressive, and lethal disease. There is a signif...

Dysregulated STAT3 Signaling Induces and Reinforces Fibroblast Senescence in Lung Fibroblasts of IPF Patients

Waters, D.W.
Schuliga, M.
Fogarty, E.
Burgess, J.K.
Grainge, C.
Westall, G.
Laurent, G.
Prêle, C.M.
Mutsaers, S.E.
Knight, D.

January 2017

American Thoracic Society International Conference Abstracts > A74. REGULATORY MECHANISMS OF THE MOL...

Reduced SOCS1 expression in lung fibroblasts from patients with IPF is not mediated by promoter methylation or Mir155

Prêle, C.M.
Iosifidis, T.
McAnulty, R.J.
Pearce, D.R.
Badrian, B.
Miles, T.
Jamieson, S.E.
Ernst, M.
Thompson, P.J.
Laurent, G.J.
Knight, D.A.
Mutsaers, S.E.

January 2021

The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transc...

Pathophysiological Roles of Stress-Activated Protein Kinases in Pulmonary Fibrosis

Yoshitoshi Kasuya
Jun-Dal Kim
Masahiko Hatano
Koichiro Tatsumi
Shuichi Matsuda

June 2021

Idiopathic pulmonary fibrosis (IPF) is one of the most symptomatic progressive fibrotic lung disease...

An Update on the Global Idiopathic Pulmonary Fibrosis (IPF) Collaborative Network: A Platform for IPF Genetics

Walker, T.
Schwartz, D.A.
Schwarz, M.I.
Fingerlin, T.E.
Powers, J.
de Andrade, J.A.
Bendstrup, E.
Blackwell, T.S.
Borie, R.
Brown, K.K.
Christie, J.D.
Collard, H.R.
Corte, T.J.
Crestani, B.
Eickelberg, O.
Gibson, K.F.
Gudmundsson, G.
Henry, M.
Hirani, N.
Inoue, Y.
Jenkins, R.G.
Kass, D.
Kawut, S.M.
Keane, J.M.
Kennedy, M.P.
Laurent, G.J.
Lederer, D.J.
Loyd, J.E.
Mogulkoc, N.
Musani, A.I.
Molina, J.
Nathan, S.D.
Noth, I.
Ohta, K.
Parfrey, H.
Poletti, V.
Prêle, C.
Ryerson, C.J.
Selman, M.
Shea, B.
Song, J.W.
Steele, M.P.
Sterclova, M.
Tobin, M.D.
Tomassetti, S.
Tobin, M.D.
Vašáková, M.
Waltz, A.
Wolters, P.J.
Zhang, Y.

January 2018

American Thoracic Society International Conference Abstracts > C72. PULMONARY FIBROSIS: MECHANISMS A...

STAT3 in tissue fibrosis: Is there a role in the lung?

Knight, D.
Mutsaers, S.E.
Prêle, C.M.

January 2011

Fibrosis is defined as an excessive deposition of connective tissue components that results in the d...

Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis.

Agostini, Carlo
Gurrieri, C.

January 2006

Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible fibrosing lung disease of unkn...

The Global Idiopathic Pulmonary Fibrosis (IPF) Collaborative Network: A Platform for IPF Genetics

Walker, T.D.
de Andrade, J.A.
Bendstrup, E.
Blackwell, T.S.
Borie, R.
Brown, K.K.
Christie, J.D.
Collard, H.R.
Corte, T.J.
Crestani, B.
Du Bois, R.M.
Eickelberg, O.
Gibson, K.F.
Henry, M.
Gudmundsson, G.
Hirani, N.
Inoue, Y.
Jenkins, R.G.
Kass, D.
Kawut, S.M.
Keane, J.M.
Kim, D.S.
Laurent, G.
Lederer, D.J.
Loyd, J.E.
Mogulkoc, N.
Molina-Molina, M.
Nathan, S.
Noth, I.
Ohta, K.
Parfrey, H.
Prêle, C.M.
Selman, M.
Song, J.W.
Sterclova, M.
Tobin, M.D.
Vašáková, M.
Wolters, P.J.
Powers, J.
Waltz, A.
Schwarz, M.I.
Schwartz, D.A.

January 2017

American Thoracic Society International Conference Abstracts > C101. IPF: CLINICAL STUDIES, THERAPEU...

Localization of activated, phosphorylated STAT3 in fibroblast foci and overlying bronchiolar epithelium in idiopathic pulmonary fibrosis (IPF) lungs.

Martina Korfei (2202892)
Daniel Stelmaszek (6014096)
BreAnne MacKenzie (158285)
Sylwia Skwarna (6014099)
Shashipavan Chillappagari (6014102)
Anna C. Bach (6014105)
Clemens Ruppert (33937)
Shigeki Saito (560645)
Poornima Mahavadi (2202901)
Walter Klepetko (110147)
Ludger Fink (5496)
Werner Seeger (5494)
Joseph A. Lasky (363234)
Soni S. Pullamsetti (6014108)
Oliver H. Krämer (166933)
Andreas Guenther (33941)

November 2018

Representative immunohistochemistry for α-SMA, phosphorylated (p)-STAT3 (Y705) and cytokeratin-5 (KR...

STAT3-Mediated signaling dysregulates lung Fibroblast-Myofibroblast activation and differentiation in UIP/IPF

Pechkovsky, D.V.
Prêle, C.M.
Wong, J.
Hogaboam, C.M.
McAnulty, R.J.
Laurent, G.J.
Zhang, S.S-M
Selman, M.
Mutsaers, S.E.
Knight, D.A.

January 2012

STAT3 is a latent transcription factor that plays a role in regulating fibroblast function in fibrot...

SOCS-Regulation of Jak/STAT Signalling in Idiopathic Pulmonary Fibrosis (IPF)

Abstract

Extracted data

SOCS-Regulation of Jak/STAT Signalling in Idiopathic Pulmonary Fibrosis (IPF)

Abstract

Extracted data

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