Nanocoral Ag for nonenzymatic glucose detection at extremely low operational potential

Silver (Ag) metal has excellent antibacterial properties, which makes it an ideal candidate for nonenzymatic glucose sensing devices. However, Ag nonenzymatic glucose sensors function at significantly high operating potential and suffer from poor selectivity. Here, we report that nanocoral reduced Ag (R-Ag) based nonenzymatic glucose sensors can be operated at potential as low as 0.1 V vs. Ag/AgCl and exhibits more than one order magnitude higher sensitivity in comparison to the Ag film. The R-Ag sensors can detect glucose in a wide range of concentrations varying from 100 u M to 2.5 mM linearly. The R-Ag sensors are also very robust, as performance remains unchanged even if sensors are stored under ambient conditions for 45 days.B.K. and J. H. designed and supervised manuscript. J. H. and A.H. prepared the sensors and J.H. performed all sensing experiments. W.C. and J.H. perform SEM, EDS and XRD experiments and H.E. analyzed the material characterization data. J. H., and B.K. wrote the manuscript and G.S. assisted with data interpretation. All authors reviewed the manuscript. All authors have also read and approved the final manuscript. K.S. efforts were supported by the NPRP11S-0110-180247 , Qatar national foundation , respectively. B.K. efforts were supported by the Office of Naval Research ( N00014-17-1-2331 ) grant, NPRP11S-0110-180247, Qatar national foundation grant National Science Foundaion-major research instrument grant ( N 1920108 ) and Department of national Nuclear Security Administration grant ( NA0003979 ) awarded to Elizabeth City State University, respectively.Scopu