Effect of vitamin D 3 supplementation on cardiometabolic disease risk among overweight/obese adult males in the UK: A pilot randomised controlled trial

From Wiley via Jisc Publications RouterHistory: received 2021-08-30, accepted 2022-04-15, pub-electronic 2022-05-09Article version: VoRPublication status: PublishedAbstract: Background: Observational studies suggest links between reduced serum 25(OH)D concentration and increased cardiometabolic disease risk. However, these studies provide limited evidence of causation, with few conclusive randomised controlled trials (RCT) having been carried out to date. This RCT investigated the effect of vitamin D3 supplementation on vascular function and cardiometabolic disease risk markers, in 55 healthy males aged 18–65 years with plasma 25(OH)D concentration